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Journal Article 2005-08-19

Autor: Bishop, Richard P. Shah, Tushaar Pelle, Roger Hoyle, D. Pearson, T. Haines, L. Brass, A. Hulme, H. Graham, S.P. Taracha, E.L.N. Lu, C. Hass, B. Wortman, J. White, O. Gardner, M.J. Nene, Vishvanath Villiers, Etienne P. de

Massively parallel signature sequencing (MPSS) was used to analyze the transcriptome of the intracellular protozoan Theileria parva. In total 1 095 000, 20 bp sequences representing 4371 different signatures were generated from T.parva schizonts. Reproducible signatures were identified within 73%...

Enlace original: https://cgspace.cgiar.org/handle/10568/21180

Investigación en Agricultura
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Bishop, Richard P. ,  Shah, Tushaar ,  Pelle, Roger ,  Hoyle, D. ,  Pearson, T. ,  Haines, L. ,  Brass, A. ,  Hulme, H. ,  Graham, S.P. ,  Taracha, E.L.N. ,  Lu, C. ,  Hass, B. ,  Wortman, J. ,  White, O. ,  Gardner, M.J. ,  Nene, Vishvanath ,  Villiers, Etienne P. de ,  [Analysis of the transcriptome of the protozoan Theileria parva using MPSS reveals that the majority of genes are transcriptionally active in the schizont stage] ,  Analysis of the transcriptome of the protozoan Theileria parva using MPSS reveals that the majority of genes are transcriptionally active in the schizont stage
Journal Article 2008-02-15

Autor: Akoolo, L. Pelle, Roger Saya, R. Awino, Elias Nyanjui, J. Taracha, E.L.N. Kanyari, P. Mwangi, D.M. Graham, S.P.

East Coast fever (ECF) is a highly fatal lymphoproliferative disease of cattle caused by Theileria parva, a tick-borne intracellular apicomplexan parasite. Parasite antigens that are targets of protective cytotoxic T lymphocyte (CTL) responses are required to formulate a sub-unit vaccine against ...

Enlace original: https://cgspace.cgiar.org/handle/10568/1942

Investigación en Agricultura
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Akoolo, L. ,  Pelle, Roger ,  Saya, R. ,  Awino, Elias ,  Nyanjui, J. ,  Taracha, E.L.N. ,  Kanyari, P. ,  Mwangi, D.M. ,  Graham, S.P. ,  [Evaluation of the recognition of Theileria parva vaccine candidate antigens by cytotoxic T lymphocytes from Zebu cattle] ,  Evaluation of the recognition of Theileria parva vaccine candidate antigens by cytotoxic T lymphocytes from Zebu cattle
Journal Article 2009-03-15

Autor: Graham, S.P. Pelle, Roger Villiers, Etienne P. de Yamage, M. Mwangi, D.M. Honda, Y. Ellis, S.A. MacHugh, Niall D. Morrison, W. Ivan Taracha, E.L.N.

Immunity against the bovine intracellular protozoan parasite Theileria parva has been shown to be mediated through the destruction of parasite infected lymphocytes by MHC class I restricted CD8+ CTL. Six parasite proteins targeted by CTL from T. parva immune cattle have been identified and raised...

Enlace original: https://cgspace.cgiar.org/handle/10568/32

Investigación en Agricultura
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Graham, S.P. ,  Pelle, Roger ,  Villiers, Etienne P. de ,  Yamage, M. ,  Mwangi, D.M. ,  Honda, Y. ,  Ellis, S.A. ,  MacHugh, Niall D. ,  Morrison, W. Ivan ,  Taracha, E.L.N. ,  [Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva] ,  Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva
Journal Article 2004

Autor: Ebel, T. Pelle, Roger Janoo, R.T.K. Lipp, J. Bishop, Richard P.

Recent studies suggest that peptidyl-prolyl isomerases of the cyclophilin family, that access the secretory pathway, can be involved in the interaction of parasitic protozoa with mammalian host cells. The amino acid sequence of a cDNA encoding a cyclophilin family member of the intracellular pro...

Enlace original: https://cgspace.cgiar.org/handle/10568/33235

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Ebel, T. ,  Pelle, Roger ,  Janoo, R.T.K. ,  Lipp, J. ,  Bishop, Richard P. ,  [A membrane-anchored Theileria parva cyclophilin with a non-cleaved amino-terminal signal peptide for entry into the endoplasmic reticulum] ,  A membrane-anchored Theileria parva cyclophilin with a non-cleaved amino-terminal signal peptide for entry into the endoplasmic reticulum
Journal Article 2016-02-20

Autor: Tretina, K. Pelle, Roger Silva, J.C.

Background Theileria parva is an intracellular parasite that causes a lymphoproliferative disease in cattle. It does so by inducing cancer-like phenotypes in the host cells it infects, although the molecular and regulatory mechanisms involved remain poorly understood. RNAseq data, and the resulti...

Enlace original: https://cgspace.cgiar.org/handle/10568/82993

Investigación en Agricultura
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Tretina, K. ,  Pelle, Roger ,  Silva, J.C. ,  [Cis regulatory motifs and antisense transcriptional control in the apicomplexan Theileria parva] ,  Cis regulatory motifs and antisense transcriptional control in the apicomplexan Theileria parva
Journal Article 2011-09-15

Autor: Celik, V. Icen, I. Pelle, Roger Munzuroglu, O. Geckil, H.
Enlace original: https://cgspace.cgiar.org/handle/10568/5421

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Celik, V. ,  Icen, I. ,  Pelle, Roger ,  Munzuroglu, O. ,  Geckil, H. ,  [Expression of gene encoding Theileria parva enolase in Escherichia coli JM103 strain] ,  Expression of gene encoding Theileria parva enolase in Escherichia coli JM103 strain
Conference Paper 2006

Autor: Mwangi, D.M. Graham, S.P. Pelle, Roger Honda, Y. Tonukari, N.J. Yamage, I.M. Glew, E.J. Villiers, Etienne P. de Shah, Tushaar Bishop, Richard P. Abuya, E. Awino, Elias Gachanja, J. Luyai, A.E. Mbwika, F. Muthiani, A.M. Ndegwa, D.M. Njahira, Moses N. Nyanjui, J.K. Onono, F.O. Osaso, J. Saya, R.M. Wildmann, C. Fraser, C.M. Maudlin, I. Gardner, M.J. Morzaria, S.P. Loosmore, S. Gilbert, S.C. Audonnet, J.C. Bruggen, P. van der Nene, Vishvanath Taracha, E.L.N.

Theileria parva, a tick-borne api-complexan protozoan parasite, causes East Coast fever (ECF) in cattle. Control of the disease by improved vaccination is believed to provide a sustainable solution. Class I MHC-restricted CD8+ cytotoxic T lymphocytes (CTL) directed at schizontinfected cells const...

Enlace original: https://cgspace.cgiar.org/handle/10568/50513

Investigación en Agricultura
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Mwangi, D.M. ,  Graham, S.P. ,  Pelle, Roger ,  Honda, Y. ,  Tonukari, N.J. ,  Yamage, I.M. ,  Glew, E.J. ,  Villiers, Etienne P. de ,  Shah, Tushaar ,  Bishop, Richard P. ,  Abuya, E. ,  Awino, Elias ,  Gachanja, J. ,  Luyai, A.E. ,  Mbwika, F. ,  Muthiani, A.M. ,  Ndegwa, D.M. ,  Njahira, Moses N. ,  Nyanjui, J.K. ,  Onono, F.O. ,  Osaso, J. ,  Saya, R.M. ,  Wildmann, C. ,  Fraser, C.M. ,  Maudlin, I. ,  Gardner, M.J. ,  Morzaria, S.P. ,  Loosmore, S. ,  Gilbert, S.C. ,  Audonnet, J.C. ,  Bruggen, P. van der ,  Nene, Vishvanath ,  Taracha, E.L.N. ,  [Exploiting host immunity and parasite genomics to develop a robust sub-unit vaccine against East Coast fever in cattle - Where are we?] ,  Exploiting host immunity and parasite genomics to develop a robust sub-unit vaccine against East Coast fever in cattle - Where are we?
Journal Article 2009-07-15

Autor: Tinega, A.N. Pelle, Roger Kang'a, S. Gicheru, M.M. Taracha, E.L.N. Nene, Vishvanath Graham, S.P.

Immunity to the bovine apicomplexan parasite Theileria parva is associated with MHC-I restricted CD8+ T cell responses directed against the intralymphocytic schizont stage of the parasite. A number of schizont-stage antigens that are targets of CD8+ T cell responses from immune animals have been ...

Enlace original: https://cgspace.cgiar.org/handle/10568/50

Investigación en Agricultura
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Tinega, A.N. ,  Pelle, Roger ,  Kang'a, S. ,  Gicheru, M.M. ,  Taracha, E.L.N. ,  Nene, Vishvanath ,  Graham, S.P. ,  [Fusion of a cell penetrating peptide from HIV-1 TAT to the Theileria parva antigen Tp2 enhances the stimulation of bovine CD8+ T cell responses] ,  Fusion of a cell penetrating peptide from HIV-1 TAT to the Theileria parva antigen Tp2 enhances the stimulation of bovine CD8+ T cell responses
Journal Article 2008-02-15

Autor: Graham, S.P. Pelle, Roger Yamage, M. Mwangi, D.M. Honda, Y. Mwakubambanya, R.S. Villiers, Etienne P. de Abuya, E. Awino, Elias Gachanja, J. Mbwika, F. Muthiani, A.M. Muriuki, C. Nyanjui, J.K.

Immunity against the bovine intracellular protozoan parasite Theileria parva has been shown to be mediated by CD8 T cells. Six antigens targeted by CD8 T cells from T. parva-immune cattle of different major histocompatibility complex (MHC) genotypes have been identified, raising the prospect of d...

Enlace original: https://cgspace.cgiar.org/handle/10568/1480

Investigación en Agricultura
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Graham, S.P. ,  Pelle, Roger ,  Yamage, M. ,  Mwangi, D.M. ,  Honda, Y. ,  Mwakubambanya, R.S. ,  Villiers, Etienne P. de ,  Abuya, E. ,  Awino, Elias ,  Gachanja, J. ,  Mbwika, F. ,  Muthiani, A.M. ,  Muriuki, C. ,  Nyanjui, J.K. ,  [Characterization of the fine specificity of Bovine CD8 T-Cell responses to defined antigens from the protozoan parasite Theileria parva] ,  Characterization of the fine specificity of Bovine CD8 T-Cell responses to defined antigens from the protozoan parasite Theileria parva

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