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Journal Article 2016-05-15

Autor: Dinga, J.N. Njimoh, D.L. Kiawa, B. Djikeng, Appolinaire Nyasa, R.B. Nkuo-Akenji, T. Pelle, Roger Titanji, V.P.K.

The development of a sterilizing and cost-effective vaccine against malaria remains a major problem despite recent advances. In this study, it is demonstrated that two antigens of P. falciparum UB05, UB09 and their chimera UB05-09 can serve as protective immunity markers by eliciting higher T-cel...

Enlace original: https://cgspace.cgiar.org/handle/10568/82985

Investigación en Agricultura
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Dinga, J.N. ,  Njimoh, D.L. ,  Kiawa, B. ,  Djikeng, Appolinaire ,  Nyasa, R.B. ,  Nkuo-Akenji, T. ,  Pelle, Roger ,  Titanji, V.P.K. ,  [Differential T-cell responses to a chimeric Plasmodium falciparum antigen; UB05-09, correlates with acquired immunity to malaria] ,  Differential T-cell responses to a chimeric Plasmodium falciparum antigen; UB05-09, correlates with acquired immunity to malaria
Journal Article 2009-07-15

Autor: Tinega, A.N. Pelle, Roger Kang'a, S. Gicheru, M.M. Taracha, E.L.N. Nene, Vishvanath Graham, S.P.

Immunity to the bovine apicomplexan parasite Theileria parva is associated with MHC-I restricted CD8+ T cell responses directed against the intralymphocytic schizont stage of the parasite. A number of schizont-stage antigens that are targets of CD8+ T cell responses from immune animals have been ...

Enlace original: https://cgspace.cgiar.org/handle/10568/50

Investigación en Agricultura
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Tinega, A.N. ,  Pelle, Roger ,  Kang'a, S. ,  Gicheru, M.M. ,  Taracha, E.L.N. ,  Nene, Vishvanath ,  Graham, S.P. ,  [Fusion of a cell penetrating peptide from HIV-1 TAT to the Theileria parva antigen Tp2 enhances the stimulation of bovine CD8+ T cell responses] ,  Fusion of a cell penetrating peptide from HIV-1 TAT to the Theileria parva antigen Tp2 enhances the stimulation of bovine CD8+ T cell responses
Journal Article 2018-03-15

Autor: Nyagwange, James Tijhaar, Edwin Ternette, Nicola Mobegi, Fredrick Tretina, Kyle Silva, Joana C. Pelle, Roger Nene, Vishvanath

East Coast fever is a lymphoproliferative disease caused by the tick-borne protozoan parasite Theileria parva. The sporozoite stage of this parasite, harboured and released from the salivary glands of the tick Rhipicephalus appendiculatus during feeding, invades and establishes infection in bovin...

Enlace original: https://cgspace.cgiar.org/handle/10568/89911

Investigación en Agricultura
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Nyagwange, James ,  Tijhaar, Edwin ,  Ternette, Nicola ,  Mobegi, Fredrick ,  Tretina, Kyle ,  Silva, Joana C. ,  Pelle, Roger ,  Nene, Vishvanath ,  [Characterization of the Theileria parva sporozoite proteome] ,  Characterization of the Theileria parva sporozoite proteome
Poster 2016-05-22

Autor: Nyagwange, James Ternette, Nicola Tijhaar, Edwin Pelle, Roger Nene, Vishvanath
Enlace original: https://cgspace.cgiar.org/handle/10568/75993

Investigación en Agricultura
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Nyagwange, James ,  Ternette, Nicola ,  Tijhaar, Edwin ,  Pelle, Roger ,  Nene, Vishvanath ,  [Proteomics of Theileria parva sporozoites] ,  Proteomics of Theileria parva sporozoites
Journal Article 2012-09-23

Autor: Henson, S. Bishop, Richard P. Morzaria, S.P. Spooner, P.R. Pelle, Roger Poveda, L. Ebeling, M. Kung, E. Certa, U. Daubenberger, C.A. Weihong Qi

Background Theileria parva is a tick-borne protozoan parasite, which causes East Coast Fever, a disease of cattle in sub-Saharan Africa. Like Plasmodium falciparum, the parasite undergoes a transient diploid life-cycle stage in the gut of the arthropod vector, which involves an obligate sexual cy...

Enlace original: https://cgspace.cgiar.org/handle/10568/24840

Investigación en Agricultura
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Henson, S. ,  Bishop, Richard P. ,  Morzaria, S.P. ,  Spooner, P.R. ,  Pelle, Roger ,  Poveda, L. ,  Ebeling, M. ,  Kung, E. ,  Certa, U. ,  Daubenberger, C.A. ,  Weihong Qi ,  [High-resolution genotyping and mapping of recombination and gene conversion in the protozoan Theileria parva using whole genome sequencing] ,  High-resolution genotyping and mapping of recombination and gene conversion in the protozoan Theileria parva using whole genome sequencing
Journal Article 2018-09-15

Autor: Sitt, T. Pelle, Roger Chepkwony, M.C. Morrison, W. Ivan Toye, Philip G.
Enlace original: https://cgspace.cgiar.org/handle/10568/98857

Investigación en Agricultura
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Sitt, T. ,  Pelle, Roger ,  Chepkwony, M.C. ,  Morrison, W. Ivan ,  Toye, Philip G. ,  [Theileria parva antigens recognized by CD8+ T cells show varying degrees of diversity in buffalo-derived infected cell lines] ,  Theileria parva antigens recognized by CD8+ T cells show varying degrees of diversity in buffalo-derived infected cell lines
Journal Article 2019-04-01

Autor: Nyagwange, James Awino, Elias Tijhaar, Edwin Svitek, Nicholas Pelle, Roger Nene, Vishvanath
Enlace original: https://cgspace.cgiar.org/handle/10568/99526

Investigación en Agricultura
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Nyagwange, James ,  Awino, Elias ,  Tijhaar, Edwin ,  Svitek, Nicholas ,  Pelle, Roger ,  Nene, Vishvanath ,  [Leveraging the Medicines for Malaria Venture malaria and pathogen boxes to discover chemical inhibitors of East Coast fever] ,  Leveraging the Medicines for Malaria Venture malaria and pathogen boxes to discover chemical inhibitors of East Coast fever
Journal Article 2018-05-15

Autor: Salih, Diaeldin A. Mwacharo, Joram M. Pelle, Roger Njahira, Moses N. Odongo, David O. Mbole-Kariuki, Mary N. Marcellino, Wani L. Malak, Agol K. Kiara, Henry K. El Hussein, A.R.M. Bishop, Richard P. Skilton, Robert A.

Theileria parva is a parasitic protozoan that causes East Coast fever (ECF), an economically important disease of cattle in eastern, central and southern Africa. In South Sudan, ECF is considered a major constraint for livestock development in regions where the disease is endemic. To obtain insig...

Enlace original: https://cgspace.cgiar.org/handle/10568/92523

Investigación en Agricultura
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Salih, Diaeldin A. ,  Mwacharo, Joram M. ,  Pelle, Roger ,  Njahira, Moses N. ,  Odongo, David O. ,  Mbole-Kariuki, Mary N. ,  Marcellino, Wani L. ,  Malak, Agol K. ,  Kiara, Henry K. ,  El Hussein, A.R.M. ,  Bishop, Richard P. ,  Skilton, Robert A. ,  [Genetic diversity and population structure of Theileria parva in South Sudan] ,  Genetic diversity and population structure of Theileria parva in South Sudan

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