The expression and characterization of a recombinant antigen termed Ov-47 are described. Ov-47 was identified and isolated from a lambda gt-11 eDNA expression library derived from adult female Onclrucercu volvukrs mRNA using rabbit antiserum raised against the surface proteins of O. vulvulcw fema...
Ghoyomu, S.M.
,
Souopgui, J.
,
Pelle, Roger
,
Titanji, V.P.K.
,
[Expression and characterization of Ov-47, a dominant antigen of Onchocerca volvulus]
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Expression and characterization of Ov-47, a dominant antigen of Onchocerca volvulus
Masake, R.A.
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Nantulya, V.M.
,
Pelle, Roger
,
Makau, J.M.
,
Gathuo, H.K.W.
,
Ole-MoiYoi, O.K.
,
[A species-specific antigen of Trypanosoma (Duttonella) vivax detectable in the course of infection is encoded by a differentially-expressed tandemly reiterated gene]
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A species-specific antigen of Trypanosoma (Duttonella) vivax detectable in the course of infection is encoded by a differentially-expressed tandemly reiterated gene
Objective: To determine the role of an immunodominant antigen OvPG-1 in human onchocerciasis. Design: Cross-sectional study of subjects living in three onchocerciasis endemic areas. Setting: Mbonge and Tubah divisions of Western Cameroon and in Esmeralda Province of Ecuador. Subjects: There were ...
Immunity against the bovine intracellular protozoan parasite Theileria parva has been shown to be mediated through the destruction of parasite infected lymphocytes by MHC class I restricted CD8+ CTL. Six parasite proteins targeted by CTL from T. parva immune cattle have been identified and raised...
Graham, S.P.
,
Pelle, Roger
,
Villiers, Etienne P. de
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Yamage, M.
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Mwangi, D.M.
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Honda, Y.
,
Ellis, S.A.
,
MacHugh, Niall D.
,
Morrison, W. Ivan
,
Taracha, E.L.N.
,
[Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva]
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Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva
The development of a sterilizing and cost-effective vaccine against malaria remains a major problem despite recent advances. In this study, it is demonstrated that two antigens of P. falciparum UB05, UB09 and their chimera UB05-09 can serve as protective immunity markers by eliciting higher T-cel...
Immunity against the bovine intracellular protozoan parasite Theileria parva has been shown to be mediated by CD8 T cells. Six antigens targeted by CD8 T cells from T. parva-immune cattle of different major histocompatibility complex (MHC) genotypes have been identified, raising the prospect of d...
Graham, S.P.
,
Pelle, Roger
,
Yamage, M.
,
Mwangi, D.M.
,
Honda, Y.
,
Mwakubambanya, R.S.
,
Villiers, Etienne P. de
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Abuya, E.
,
Awino, Elias
,
Gachanja, J.
,
Mbwika, F.
,
Muthiani, A.M.
,
Muriuki, C.
,
Nyanjui, J.K.
,
[Characterization of the fine specificity of Bovine CD8 T-Cell responses to defined antigens from the protozoan parasite Theileria parva]
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Characterization of the fine specificity of Bovine CD8 T-Cell responses to defined antigens from the protozoan parasite Theileria parva