Cattle from 50 farms in Mukono County, Uganda, were monitored for trypanosomes every second month over an 18-month period (1995–1996) by mini-anion exchange chromatography and haematocrit centrifugation techniques. Eighteen trypanosome isolates collected from cattle during this period were charac...
Olila, D.
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McDermott, John J.
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Eisler, M.C.
,
Mitema, E.S.
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Patzelt, R.J.
,
Clausen, P.H.
,
Poetzsch, C.J.
,
Zessin, K.H.
,
Mehlitz, D.
,
Peregrine, A.S.
,
[Drug sensitivity of trypanosome populations from cattle in a peri-urban dairy production system in Uganda]
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Drug sensitivity of trypanosome populations from cattle in a peri-urban dairy production system in Uganda
The frequency of trypanosomes resistant to diminazene aceturate at a dose of 26 mg/kg of bwt was investigated for populations of Trypanosoma congolense IL 3274 which reappeared in infected mice after intraperitoneal treatment with diminazene aceturate at the same dosage. At inoculum sizes of 102,...
Mamman, M.
,
Gettinby, N.B.
,
Murphy, N.B.
,
Kemei, S.
,
Peregrine, A.S.
,
[Frequency of diminazene - resistant trypanosomes in populations of Trypanosoma congolense arising in infected animals following treatment with diminazene aceturate]
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Frequency of diminazene - resistant trypanosomes in populations of Trypanosoma congolense arising in infected animals following treatment with diminazene aceturate
Peregrine, A.S.
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Knowles, G.
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Ibitayo, A.I.
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Scott, J.R.
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Moloo, S.K.
,
Murphy, N.B.
,
[Variation in resistance to isometamidium chloride and diminazene aceturate by clones derived from a stock of Trypanosoma congolense]
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Variation in resistance to isometamidium chloride and diminazene aceturate by clones derived from a stock of Trypanosoma congolense
Zilberstein, D.
,
Wilkes, J.M.
,
Hirumi, H.
,
Peregrine, A.S.
,
[Fluorescence analysis of the interaction of isometamidium with Trypanosoma congolense]
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Fluorescence analysis of the interaction of isometamidium with Trypanosoma congolense
Diminazene aceturate is one of a limited number of drugs currently being used in animals to treat the tsetse fly-transmitted protozoal disease, African trypanosomiasis. Efficacy of the drug at the recommended single IM administered doses of 3.5 and 7.0 mg/kg of body weight is widely acknowledged....
Mamman, M.
,
McKeever, Declan J.
,
Aliu, Y.O.
,
Peregrine, A.S.
,
[Pharmacokinetics of diminazene in plasma and lymph of goats]
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Pharmacokinetics of diminazene in plasma and lymph of goats
Peregrine, A.S.
,
Hirumi, H.
,
Zilberstein, D.
,
[Fluorescence analysis of the interaction of isometamidium (Samorin) with Trypanosoma congolense]
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Fluorescence analysis of the interaction of isometamidium (Samorin) with Trypanosoma congolense
In 1986 a project was set up to determine the constraints to production of Zebu cattle under trypanosomiasis risk in the Ghibe valley. Approximately 1800 East African Zebu cattle (EAZC) were resident within the Ghibe valleey during the experimental period (1986 - 1992) and were maintained under t...
Peregrine, A.S.
,
Mulatu, W.
,
Leak, S.G.A.
,
Rowlands, G.J.
,
[Epidemiology of bovine trypanosomiasis in the Ghibe Valley, Ethiopia: Multiple-drug resistance and its effective control]
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Epidemiology of bovine trypanosomiasis in the Ghibe Valley, Ethiopia: Multiple-drug resistance and its effective control
Peregrine, A.S.
,
Ogunyemi, O.
,
Bell, I.R.
,
Holmes, P.H.
,
Moloo, S.K.
,
Hirumi, H.
,
Murray, M.
,
Urquhart, G.M.
,
Whitelaw, D.D.
,
[Isometamidium chloride (Samorin) chemoprophylaxis. A study into factors that may influence the apparent duration of prophylaxis]
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Isometamidium chloride (Samorin) chemoprophylaxis. A study into factors that may influence the apparent duration of prophylaxis