Control of trypanosomes in cattle, sheep and goats in endemic areas has depended largely on the use of chemotherapeutic or chemoprophylactic agents. One such agent is homidium. The normal use of homidium has been in the treatment of infections due to both Trypanosoma congolense and T.vivax in cat...
Murilla, G.A.
,
Peregrine, A.S.
,
Holmes, P.H.
,
Eisler, M.C.
,
Ndung'u, J.M.
,
[Investigation into the effects of Trypanosoma congolense infections on the pharmacokinetics of Homidium in Boran cattle]
,
Investigation into the effects of Trypanosoma congolense infections on the pharmacokinetics of Homidium in Boran cattle
Control of trypanosomosis in cattle, sheep and goats in endemic areas has depended largely on the use of chemotherapeutic or chemoprophylactic agents. One such agent is homidium. The normal use of homidium has been in the treatment of infections due to both Trypanosoma congolense and T. vivax in ...
Murilla, G.
,
Peregrine, A.S.
,
Holmes, P.H.
,
Eisler, M.C.
,
Ndung'u, J.M.
,
[Investigation into the effects of Trypanosoma congolense infections on the pharmacokinetics of Homidium in Boran cattle]
,
Investigation into the effects of Trypanosoma congolense infections on the pharmacokinetics of Homidium in Boran cattle
The FAO/IAEA Trypanosomiasis Direct Antigen-ELISA kit has been distributed to scientists holding research contracts under an IAEA Co-ordinated Research Programme in 14 sub-Saharan African countries. It is intended for improved diagnosis of bovine tsetse-transmitted trypanosomiasis as an aid to e...
Eisler, M.C.
,
Lessard, P.
,
Moloo, D.
,
Masake, R.A.
,
Peregrine, A.S.
,
[Sensitivity and specificity of antigen-capture ELISAs for diagnosis of Trypanosoma congolense and Trypanosoma vivax infections in cattle]
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Sensitivity and specificity of antigen-capture ELISAs for diagnosis of Trypanosoma congolense and Trypanosoma vivax infections in cattle
Tsetse-transmitted trypanosomosis affects cattle production over approximately 10 million km2 of Africa. In these areas, trypanocidal drugs, both prophylactic and curative, are the most widely used methods of trypanosomosis control. However, resistance of trypanosomes to the 3 trypanocidal drugs ...
McDermott, John J.
,
Coleman, P.G.
,
Eisler, M.C.
,
Peregrine, A.S.
,
[The effects of resistance to trypanocidal drugs on trypanosome transmission]
,
The effects of resistance to trypanocidal drugs on trypanosome transmission
The extent and significance of trypanocidal drug resistance was investigated in priority areas of three East and Southern African Countries under a project. The project was built on the results of two previous projects. Existing methods currently available for the demonstration of drug-resistance...
Eisler, M.C.
,
Ndung'u, J.M.
,
Murilla, G.
,
Mdachi, R.M.
,
Mbwambo, H.
,
Sinyangwe, L.
,
Machila, N.
,
Delespaux, V.
,
Geerts, S.
,
Brandt, J.
,
Peregrine, A.S.
,
McDermott, John J.
,
Holmes, P.H.
,
[Area-wide appraisal of drug resistance in trypanosomes infecting cattle in East and Southern Africa]
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Area-wide appraisal of drug resistance in trypanosomes infecting cattle in East and Southern Africa
It is useful to be able to estimate the incidence of new infections in cattle exposed to a high challenge of drug resistance trypanosomes; with this information the impact of an intervention that improves the control of trypanosomosis can be better understood. Approximately 750 Ethiopian Highland...
Twelve traditional herds of cattle in the area of Boundiali, northern Cote d'Ivoire, were examined monthly from 1990 to 1992 for the presence of trypanosomes. The herds were randomised into 3 treatment groups, cattle in 4 herds received diminazene aceturate at 3.5 or 7 mg/kg body weight (b.w.) wh...