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The frequency of trypanosomes resistant to diminazene aceturate at a dose of 26 mg/kg of bwt was investigated for populations of Trypanosoma congolense IL 3274 which reappeared in infected mice after intraperitoneal treatment with diminazene aceturate at the same dosage. At inoculum sizes of 102,...


Mamman, M.Gettinby, N.B.Murphy, N.B.Kemei, S.Peregrine, A.S.[Frequency of diminazene - resistant trypanosomes in populations of Trypanosoma congolense arising in infected animals following treatment with diminazene aceturate]Frequency of diminazene - resistant trypanosomes in populations of Trypanosoma congolense arising in infected animals following treatment with diminazene aceturate
Zilberstein, D.Wilkes, J.M.Hirumi, H.Peregrine, A.S.[Fluorescence analysis of the interaction of isometamidium with Trypanosoma congolense]Fluorescence analysis of the interaction of isometamidium with Trypanosoma congolense
Peregrine, A.S.Hirumi, H.Zilberstein, D.[Fluorescence analysis of the interaction of isometamidium (Samorin) with Trypanosoma congolense]Fluorescence analysis of the interaction of isometamidium (Samorin) with Trypanosoma congolense
Mamman, M.Gettinby, G.Murphy, N.B.Kemei, S.Peregrine, A.S.[Frequency of diminazene-resistant trypanosomes in populations of Trypanosoma congolense arising in infected animals following treatment with diminazene]Frequency of diminazene-resistant trypanosomes in populations of Trypanosoma congolense arising in infected animals following treatment with diminazene

During this century livestock production has increased massively through the improved ability to diagnose, treat, control and prevent certain diseases. Despite these advances, disease remains a major constraint to livestock production and welfare throughout the world. In many instances, this is a...


Gu, Y.Gettinby, G.McKendrick, I.Murray, M.Peregrine, A.S.[Development of a decision support system for trypanocidal drug control of bovine trypanosomosis in Africa]Development of a decision support system for trypanocidal drug control of bovine trypanosomosis in Africa
Peregrine, A.S.Moloo, S.K.Whitelaw, D.D.[Differences in sensitivity of Kenyan Trypanosoma vivax populations to the prophylactic and therapeutic actions of isometamidium chloride in Boran cattle]Differences in sensitivity of Kenyan Trypanosoma vivax populations to the prophylactic and therapeutic actions of isometamidium chloride in Boran cattle
Hirumi, H.Hirumi, K.Peregrine, A.S.[Axenic culture of Trypanosoma congolense: Application to the detection of sensitivity levels of bloodstream Trypomastigotes to diminazene aceturate, homidium chloride, isometamidium chloride and quinapyramine sulphate]Axenic culture of Trypanosoma congolense: Application to the detection of sensitivity levels of bloodstream Trypomastigotes to diminazene aceturate, homidium chloride, isometamidium chloride and quinapyramine sulphate

Interaction of the trypanocide isometamidium chloride with components of Trypanosoma congolense results in characteristic shifts in the intrinsic fluorescence of the drug. The specificity of this interaction was investigated by analysing the effects of various physiochemical manipulations on its ...


Wilkes, J.M.Peregrine, A.S.Zilberstein, D.[The accumulation and compartmentalization of isometamidium chloride in Trypanosoma congolense, monitored by its intrinsic fluorescence]The accumulation and compartmentalization of isometamidium chloride in Trypanosoma congolense, monitored by its intrinsic fluorescence
Ndoutamia, G.Moloo, S.K.Murphy, N.B.Peregrine, A.S.[Derivation and characterization of a quinapyramine-resistant clone of Trypanosoma congolense]Derivation and characterization of a quinapyramine-resistant clone of Trypanosoma congolense

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