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Journal Article 1995

Autor: Desquesnes, M. Rocque, S. de la Peregrine, A.S.

An isolate of T. vivax was collected from a naturally infected Zebu in French Guyana. The isolate was subsequently shown to produce pathogenic infections in both Taurine and Zebu cattle. However, its sensitivity of the population to diminazene aceturate and isometamidium chloride was determined s...

Enlace original: https://cgspace.cgiar.org/handle/10568/27978

Investigación en Agricultura
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Desquesnes, M. ,  Rocque, S. de la ,  Peregrine, A.S. ,  [French Guyanan stock of Trypanosoma vivax resistant to diminazene aceturate but sensitive to isometamidium chloride] ,  French Guyanan stock of Trypanosoma vivax resistant to diminazene aceturate but sensitive to isometamidium chloride
Journal Article 1995

Autor: Mamman, M. Williams, D.J.L. Murphy, N.B. Peregrine, A.S.

Experiments were carried out in goats to determine the frequency with which diminazene-resistant trypanosomes occur in parasite populations before and after the intramuscular treatment of the goats with diminazene aceturate. Trypanosoma congolense IL3274, a diminazene-resistant clone, was used to...

Enlace original: https://cgspace.cgiar.org/handle/10568/29557

Investigación en Agricultura
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Mamman, M. ,  Williams, D.J.L. ,  Murphy, N.B. ,  Peregrine, A.S. ,  [Apparent rarity of diminazene-resistant trypanosomes in goats infected with a diminazene-resistant population of Trypanosoma congolense] ,  Apparent rarity of diminazene-resistant trypanosomes in goats infected with a diminazene-resistant population of Trypanosoma congolense
Journal Article 1994

Autor: Peregrine, A.S. Mulatu, W. Leak, S.G.A. Rowlands, G.J.

In 1986 a project was set up to determine the constraints to production of Zebu cattle under trypanosomiasis risk in the Ghibe valley. Approximately 1800 East African Zebu cattle (EAZC) were resident within the Ghibe valleey during the experimental period (1986 - 1992) and were maintained under t...

Enlace original: https://cgspace.cgiar.org/handle/10568/29134

Investigación en Agricultura
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Peregrine, A.S. ,  Mulatu, W. ,  Leak, S.G.A. ,  Rowlands, G.J. ,  [Epidemiology of bovine trypanosomiasis in the Ghibe Valley, Ethiopia: Multiple-drug resistance and its effective control] ,  Epidemiology of bovine trypanosomiasis in the Ghibe Valley, Ethiopia: Multiple-drug resistance and its effective control
Journal Article 1999

Autor: Gu, Y. Gettinby, G. McKendrick, I. Murray, M. Peregrine, A.S.

During this century livestock production has increased massively through the improved ability to diagnose, treat, control and prevent certain diseases. Despite these advances, disease remains a major constraint to livestock production and welfare throughout the world. In many instances, this is a...

Enlace original: https://cgspace.cgiar.org/handle/10568/33251

Investigación en Agricultura
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Gu, Y. ,  Gettinby, G. ,  McKendrick, I. ,  Murray, M. ,  Peregrine, A.S. ,  [Development of a decision support system for trypanocidal drug control of bovine trypanosomosis in Africa] ,  Development of a decision support system for trypanocidal drug control of bovine trypanosomosis in Africa
Journal Article 1997

Autor: Eisler, M.C. Gault, E.A. Moloo, S.K. Holmes, P.H. Peregrine, A.S.

The relationship between serum concentrations of the prophylactic trypanocidal drug isometamidium chloride and protection against tsetse challenge with two populations of Trypanosoma congolense was investigated in Boran (Bos indicus) cattle, using an isometamidium-ELISA. Isometamidium chloride (S...

Enlace original: https://cgspace.cgiar.org/handle/10568/29975

Investigación en Agricultura
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Eisler, M.C. ,  Gault, E.A. ,  Moloo, S.K. ,  Holmes, P.H. ,  Peregrine, A.S. ,  [Concentrations of isometamidium in the sera of cattle challenged with drug-resistant Trypanosoma congolense] ,  Concentrations of isometamidium in the sera of cattle challenged with drug-resistant Trypanosoma congolense
Journal Article 1998

Autor: Diack, A. Moloo, S.K. Peregrine, A.S.

Six Boran cattle were infected with the drug-resistant Trypanosoma congolense IL 3338. At the first peak of parasitemia different groups of 200 teneral Glossina morsitans centralis were fed once on each animal, just prior to treatment with diminazene aceturate at a dose of 3.5 mg kg-1 body weight...

Enlace original: https://cgspace.cgiar.org/handle/10568/29588

Investigación en Agricultura
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Diack, A. ,  Moloo, S.K. ,  Peregrine, A.S. ,  [Effect of multiple treatment of cattle with diminazene aceturate on the infectivity and transmissibility of drug-resistant Trypanosoma congolense for Glossina morsitans centralis] ,  Effect of multiple treatment of cattle with diminazene aceturate on the infectivity and transmissibility of drug-resistant Trypanosoma congolense for Glossina morsitans centralis
Journal Article 1994

Autor: Burudi, E.M.E. Peregrine, A.S. Majiwa, P.A.O. Mbiuki, S.M. Murphy, N.B.

A study was carried out to determine whether a drug-resistant trypanosome population could influence the survival of a drug-sensitive population in mixed infections in goats. To identify both populations during the course of a mixed infection, a system for distinguishing them was developed; using...

Enlace original: https://cgspace.cgiar.org/handle/10568/28341

Investigación en Agricultura
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Burudi, E.M.E. ,  Peregrine, A.S. ,  Majiwa, P.A.O. ,  Mbiuki, S.M. ,  Murphy, N.B. ,  [Response of diminazene-resistance and diminazene-susceptible Trypanosoma congolense to treatment with diminazene when occuring as a mixed infection in goats] ,  Response of diminazene-resistance and diminazene-susceptible Trypanosoma congolense to treatment with diminazene when occuring as a mixed infection in goats
Journal Article 1997

Autor: Mulugeta, W. Wilkes, J. Mulatu, W. Majiwa, P.A.O. Masake, R. Peregrine, A.S.

Ten trypanosome isolates were collected at random from cattle at Ghibe, Ethiopia, in February 1993 and all shown to be savannah-type Trypanosoma congolense. When inoculated into naive Boran (Bos indicus) calves, all 10 isolates were resistant to diminazene aceturate (Berenil), isometamidium chlor...

Enlace original: https://cgspace.cgiar.org/handle/10568/28036

Investigación en Agricultura
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Mulugeta, W. ,  Wilkes, J. ,  Mulatu, W. ,  Majiwa, P.A.O. ,  Masake, R. ,  Peregrine, A.S. ,  [Long-term occurrence of Trypanosoma congolense resistant to diminazene, isometamidium and homidium in cattle at Ghibe, Ethiopia] ,  Long-term occurrence of Trypanosoma congolense resistant to diminazene, isometamidium and homidium in cattle at Ghibe, Ethiopia
Journal Article 1997

Autor: Wilkes, J.M. Mulugeta, W. Wells, C. Peregrine, A.S.

Bloodstream forms of four populations of the livestock pathogen Trypanosoma congolense, isolated from different natural infections, have been shown to exhibit a wide range of sensitivities to the trypanocide isometamidium chloride (Samorin). In mice the 50 percent curative doses (CD 50) for Samor...

Enlace original: https://cgspace.cgiar.org/handle/10568/30092

Investigación en Agricultura
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Wilkes, J.M. ,  Mulugeta, W. ,  Wells, C. ,  Peregrine, A.S. ,  [Modulation of mitochondrial electrical potential: A candidate mechanism for drug resistance in African trypanosomes] ,  Modulation of mitochondrial electrical potential: A candidate mechanism for drug resistance in African trypanosomes
Journal Article 1997

Autor: Peregrine, A.S. Gray, M.A. Moloo, S.K.

Resistance to isometamidium was increased 94-fold in a clone of Trypanosoma congolense (clone IL 1180) by repeated subcurative treatment of infected mice for 11 months. This was associated with 3.4-, 33-, and 4.2-fold increases in resistance to diminazene, homidium, and quinapyramine, respectivel...

Enlace original: https://cgspace.cgiar.org/handle/10568/30084

Investigación en Agricultura
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Peregrine, A.S. ,  Gray, M.A. ,  Moloo, S.K. ,  [Cross-resistance associated with development resistance to isometamidium in a clone of Trypanosoma congolense] ,  Cross-resistance associated with development resistance to isometamidium in a clone of Trypanosoma congolense

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