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In a cross-sectional study carried out in June 1994, 486 cattle from 50 randomly selected dairy farms in the vicinity of Kampala, Uganda, were examined for trypanosome infections. The trypanosome prevalence (either positive with the haematocrit centrifugation technique [HCT] and/or the mini-anion...
Trypanosomosis remains one of the biggest impediments to the Development of the livestock industry in sub-Saharan Africa while it is likely that a vaccine for this disease could be found in the future, none is presently available. Mean-while different strategies are being followed to control this...
Trypanocidal drugs are the most widely applied method of trypanosomosis control in Africa and the only control method in Latin America and Asia . Treatment recommendations and strategies for chemotherapeutic control of trypanosomosis depends on information of trypanosomosis risk and the prevalenc...
The peri-urban dairy production systems in Uganda, located in the subhumid agro-ecological zone with medium rainfall have a high potential for livestock production (Walsche et al., 1991; Winrock, 1992), but medium tsetse challenge and the associated trypanosomiasis risk may adversely affect dairy...
Studies on infections with drug-resistant trypanosomes indicate that the majority of parasites in a population are sensitive to the drug dose used to select the population (Mamman et al., 1993). This study was initiated to examine whether a drug-resistant trypanosome population could influence th...
It is useful to be able to estimate the incidence of new infections in cattle exposed to a high challenge of drug resistance trypanosomes; with this information the impact of an intervention that improves the control of trypanosomosis can be better understood. Approximately 750 Ethiopian Highland...
To investigate the importance of trypanosomosis, resistance to trypanocidal drugs and the potential impact of integrated control measures on these factors, a 3-phase study was initiated. The first phase was a cross-sectional study in which tsetse apparent density, cattle trypanosome prevalence, t...
Isometamidium chloride (Samorin, Trypanidium is a phenanthridine-aromatic amidine that is commonly used in cattle as a prophylactic agent against trypanosomiasis. Although the compound has been used for over 30 years, very little is known about its mode of action. Various workers have demonstrate...
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