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Norval, R.A.I.Peter, T.F.Sonenshine, D.E.Burridge, M.J.[Responses of the ticks Amblyomma hebraeum and A. variegatum to known or potential components of the aggregation-attachment pheromome. III. Aggregation]Responses of the ticks Amblyomma hebraeum and A. variegatum to known or potential components of the aggregation-attachment pheromome. III. Aggregation

The indirect MAP 1B ELISA based on the recombinant MAP 1B fragment of the immunodominant MAP 1 protein of Ehrlichia ruminantium is considered to be the most sensitive and specific assay for the serodiagnosis of heartwater. In this study, we evaluated its reliability in detecting exposure to E....


Peter, T.F.O'Callaghan, C.J.Medley, G.F.Perry, Brian D.Semu, S.M.Mahan, S.M.[Population-based evaluation of the Ehrlichia ruminantium MAP 1B indirect ELISA]Population-based evaluation of the Ehrlichia ruminantium MAP 1B indirect ELISA

Three species of wild African ruminants. impala (Aepyceros melampus), sable (Hippotragus equinus, and tsessebe (Damaliscus lunatus), were experimentally inoculated with in vitro culture-derived Cowdria ruminantium organisms, the tick-borne causative agent of heartwater in domestic ruminants, to d...


Peter, T.F.Anderson, E.C.Burridge, M.J.Perry, Brian D.Mahan, S.M.[Susceptibility and carrier status of impala, sable and tsessebe for Cowdria ruminantium infection (heartwater)]Susceptibility and carrier status of impala, sable and tsessebe for Cowdria ruminantium infection (heartwater)

A mathematical description of the transmission dynamics of the tick-borne infection Cowdria ruminantium in commercial beef enterprises in Zimbabwe was used to consider the potential impact of a candidate vaccine to prevent heartwater. The important characteristics of the vaccine were (1) a delay ...


O'Callaghan, C.J.Medley, G.F.Peter, T.F.Mahan, S.M.Perry, Brian D.[Predicting the effect of vaccination on the transmission dynamics of heartwater (Cowdria ruminantium infection)]Predicting the effect of vaccination on the transmission dynamics of heartwater (Cowdria ruminantium infection)

As part of a series of studies associated with the development of improved vaccines for heartwater (a tick-borne disease of ruminant livestock caused by Cowdria ruminantium), field surveys were carried out to assess losses associated with the disease and the costs associated with controlling it i...


Chamboko, TafireyiMukhebi, A.W.Callaghan, C.J.O.Peter, T.F.Kruska, R.L.Medley, G.F.Mahan, S.M.Perry, Brian D.[The control of heartwater on large-scale commercial and smallholder farms in Zimbabwe]The control of heartwater on large-scale commercial and smallholder farms in Zimbabwe

Heartwater, caused by the rickettsial organism Cowdria ruminantium, is a serious constraint to livestock development in much of sub-Saharan Africa. Traditionally, the disease has been controlled by the use of chemical acaricides to control the vector tick. The University of Florida/USAID-supporte...


Mukhebi, A.W.Chamboko, TafireyiO'Callaghan, C.J.Peter, T.F.Kruska, R.L.Medley, G.F.Mahan, S.M.Perry, Brian D.[An assessment of the economic impact of heartwater (Cowdria ruminantium infection) and its control in Zimbabwe]An assessment of the economic impact of heartwater (Cowdria ruminantium infection) and its control in Zimbabwe

Adult Amblyomma hebraeum ticks, the principle vector of heartwater (cowdriosis) of domestic ruminants in southern Africa, were collected in pheromone traps placed in Kruger National Park, an exclusively wildlife sanctuary in South Africa. These ticks transmitted Cowdria ruminantium, the rickettsi...


Peter, T.F.Bryson, N.R.Perry, Brian D.O'Callaghan, C.J.Medley, G.F.Smith, G.E.Mlambo, G.Horak, I.G.Burridge, M.J.Mahan, S.M.[Cowdria ruminantium infection in ticks in the Kruger National Park]Cowdria ruminantium infection in ticks in the Kruger National Park

The authors highlight the reliance on repeated natural infections by tickborne pathogens to maintain immunity in immunized herds. That incidence of clinical heartwater in cattle, caused by Cowdria ruminantium, is low while intensive acaricide use interrupts transmission of pathogens. Evidence is ...


Perry, Brian D.Chamboko, TafireyiMahan, S.M.Medley, G.F.Minjauw, B.O'Callaghan, C.J.Peter, T.F.[The economics of integrated tick and tick-borne disease control on commercial farms in Zimbabwe]The economics of integrated tick and tick-borne disease control on commercial farms in Zimbabwe

Analysis of the transmission dynamics of Cowdria ruminantium, the tick-borne rickettsial agent of heartwater in ruminants, requires accurate measures of infection in vector populations. To obtain these, Amblyomma hebraeum ticks were collected at two heartwater-endemic locations in the lowveld and...


Peter, T.F.Perry, Brian D.O'Callaghan, C.J.Medley, G.F.Mlambo, G.Barbet, A.F.Mahan, S.M.[Prevalence of Cowdria ruminantium infection in Amblyomma hebraeum ticks from heartwater-endemic areas of Zimbabwe]Prevalence of Cowdria ruminantium infection in Amblyomma hebraeum ticks from heartwater-endemic areas of Zimbabwe

The International Livestock Research Institute (ILRI) conducts research on strategic issues that constrain livestock productivity of resource-poor households, with a focus as smallholder crop-livestock systems. The institute conducts research in the areas of ruminant genetics, ruminant health, fe...


Perry, Brian D.Kruska, R.L.Medley, G.F.Mukhebi, A.W.O'Callaghan, C.J.Peter, T.F.Reid, Robin S.Williams, T.[Ex ante impact assessment of disease control technologies: The case of vector-borne infections in Africa]Ex ante impact assessment of disease control technologies: The case of vector-borne infections in Africa

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