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Contagious Bovine Pleuropneumonia (CBPP) is a severe respiratory disease caused byMycoplasma mycoides subsp. mycoides (Mmm) which is widespread in Africa. The capsule polysaccharide (CPS) of Mmm is one of the few identified virulence determinants. In a previous study, immunization of mice against...


Mwirigi, M.Nkando, I.Olum, M.Attah-Poku, S.Ochanda, H.Berberov, E.Potter, A.Gerdts, V.Pérez Casal, J.Wesonga, H.O.Soi, R.Naessens, Jan[Capsular polysaccharide from Mycoplasma mycoides subsp.mycoides shows potential for protection against Contagious Bovine Pleuropneumonia]Capsular polysaccharide from Mycoplasma mycoides subsp.mycoides shows potential for protection against Contagious Bovine Pleuropneumonia

Mycoplasma mycoides subsp. mycoides (Mmm) is the causative agent of contagious bovine pleuropneumonia (CBPP), a devastating respiratory disease mainly affecting cattle in sub-Saharan Africa. The current vaccines are based on live-attenuated Mmmstrains and present problems with temperature stabili...


Nkando, I.Pérez Casal, J.Mwirigi, M.Prysliak, T.Townsend, H.Berberov, E.Kuria, J.Mugambi, J.Soi, R.Liljander, Anne M.Jores, JoergGerdts, V.Potter, A.Naessens, JanWesonga, H.O.[Recombinant Mycoplasma mycoides proteins elicit protective immune responses against contagious bovine pleuropneumonia]Recombinant Mycoplasma mycoides proteins elicit protective immune responses against contagious bovine pleuropneumonia

Current contagious bovine pleuropneumonia (CBPP) vaccines are based on live-attenuated strains of Mycoplasma mycoides subsp. mycoides (Mmm). These vaccines have shortcomings in terms of efficacy, duration of immunity and in some cases show severe side effects at the inoculation site; hence the ne...


Pérez Casal, J.Prysliak, T.Maina, T.Wang, Y.Townsend, H.Berverov, E.Nkando, I.Wesonga, H.O.Liljander, Anne M.Jores, JoergNaessens, JanGerdts, V.Potter, A.[Analysis of immune responses to recombinant proteins from strains of Mycoplasma mycoides subsp. mycoides, the causative agent of contagious Bovine pleuropneumonia]Analysis of immune responses to recombinant proteins from strains of Mycoplasma mycoides subsp. mycoides, the causative agent of contagious Bovine pleuropneumonia

The current control method for contagious bovine pleuropneumonia (CBPP) in Africa is vaccination with a live, attenuated strain of Mycoplasma mycoides subsp. mycoides(Mmm). However, this method is not very efficient and often causes serious adverse reactions. Several studies have attempted to ind...


Mwirigi, M.Nkando, I.Aye, R.Soi, R.Ochanda, H.Berberov, E.Potter, A.Gerdts, V.Pérez Casal, J.Naessens, JanWesonga, H.O.[Experimental evaluation of inactivated and live attenuated vaccines against Mycoplasma mycoides subsp. Mycoides]Experimental evaluation of inactivated and live attenuated vaccines against Mycoplasma mycoides subsp. Mycoides

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