Búsqueda - Portal Conocimiento Público CL

Journal Article 2006

Gene-expression profiling discriminates between cerebral malaria (CM) - susceptible mice and CM-resistant mice

Autor: Delhaye, N.F. Coltel, N. Puthier, D. Flori, L. Houlgatte, R. Iraqi, F.A. Nguyen, C. Grau, G.E. Rihet, P.

The development of cerebral malaria (CM) in mice with Plasmodium berghei ANKA infection is under genetic control. Brain gene-expression patterns were investigated in well-defined genetically CM-resistant (CM-R; BALB/c and DBA/2) and CM-susceptible (CM-S; C57BL/6 and CBA/J) mice by use of cDNA mic...

Enlace original: https://cgspace.cgiar.org/handle/10568/29649

Investigación en Agricultura

MALARIA

GENE EXPRESSION

BRAIN

Citar Enlace permanente

Delhaye, N.F. , Coltel, N. , Puthier, D. , Flori, L. , Houlgatte, R. , Iraqi, F.A. , Nguyen, C. , Grau, G.E. , Rihet, P. , [Gene-expression profiling discriminates between cerebral malaria (CM) - susceptible mice and CM-resistant mice] , Gene-expression profiling discriminates between cerebral malaria (CM) - susceptible mice and CM-resistant mice

Journal Article 2004

Mapping of a new quantitative trait locus for resistance to malaria in mice by a comparative mapping approach with human chromosome 5q31-q33

Autor: Hernández Valladares, M. Rihet, P. Ole-MoiYoi, O.K. Iraqi, F.A.

A number of linkage studies in human populations have identified a locus ( pfbi) on Chromosome 5q31-q33 controlling Plasmodiun falciparum blood infection levels. This region contains numerous candidate genes encoding immunological molecules such as cytokines, growth factors and growth-factor rec...

Enlace original: https://cgspace.cgiar.org/handle/10568/32938

Investigación en Agricultura

MALARIA

GENETIC MAPS

GENETIC RESISTANCE

Citar Enlace permanente

Hernández Valladares, M. , Rihet, P. , Ole-MoiYoi, O.K. , Iraqi, F.A. , [Mapping of a new quantitative trait locus for resistance to malaria in mice by a comparative mapping approach with human chromosome 5q31-q33] , Mapping of a new quantitative trait locus for resistance to malaria in mice by a comparative mapping approach with human chromosome 5q31-q33

Journal Article 2005

TNF as a malaria candidate gene: Polymorphism-screening and family-based association analysis of mild malaria attack and parasitemia in Burkina Faso

Autor: Flori, L. Delahaye, N.F. Iraqi, F.A. Hernández Valladares, M. Fumoux, F. Rihet, P.

We have previously obtained strong evidence for linkage of mild malaria attack to the MHC region, with a peak close to the tumor necrosis factor (TNF) gene. We screened, for polymorphisms, the entire TNF gene in the same sample of 34 families comprising 197 individuals living in a Plasmodium falc...

Enlace original: https://cgspace.cgiar.org/handle/10568/28659

Investigación en Agricultura

MALARIA

CYTOKINES

GENES

Citar Enlace permanente

Flori, L. , Delahaye, N.F. , Iraqi, F.A. , Hernández Valladares, M. , Fumoux, F. , Rihet, P. , [TNF as a malaria candidate gene: Polymorphism-screening and family-based association analysis of mild malaria attack and parasitemia in Burkina Faso] , TNF as a malaria candidate gene: Polymorphism-screening and family-based association analysis of mild malaria attack and parasitemia in Burkina Faso

Journal Article 2004

Confirmation and dissection of QTL controlling resistance to malaria in mice

Autor: Hernández Valladares, M. Naessens, Jan Gibson, John P. Musoke, A.J. Nagda, S.M. Rihet, P. Ole-MoiYoi, O.K. Iraqi, F.A.

We developed an F(11) AIL population from an F(1) cross of A/J (susceptible) and C57BL/6J (resistant) mouse strains. One thousand F(11) mice were challenged with P.c. chabaudi 54X, and 340 mice selected from the phenotypic extremes for susceptibility and resistance were genotyped for microsatel...

Enlace original: https://cgspace.cgiar.org/handle/10568/29204

Investigación en Agricultura

MALARIA

MICE

GENETIC RESISTANCE

Citar Enlace permanente

Hernández Valladares, M. , Naessens, Jan , Gibson, John P. , Musoke, A.J. , Nagda, S.M. , Rihet, P. , Ole-MoiYoi, O.K. , Iraqi, F.A. , [Confirmation and dissection of QTL controlling resistance to malaria in mice] , Confirmation and dissection of QTL controlling resistance to malaria in mice

Journal Article 2004

Comparison of pathology in susceptible A/J and resistant C57BL/6J mice after infection with different sub-strains of Plasmodium chabaudi

Autor: Hernández Valladares, M. Naessens, Jan Nagda, S.M. Musoke, A.J. Rihet, P. Ole-MoiYoi, O.K. Iraqi, F.A.

Susceptible A/J and more resistant C57BL/6J mice were infected with Plasmodium chabaudi chabaudi 54X, P.c. chabaudi AS and Plasmodium chabaudi adami 408XZ. As expected, most C57BL/6J mice survived the infections with the different isolates. But in contrast to previous observations, not all A/J ...

Enlace original: https://cgspace.cgiar.org/handle/10568/32918

Investigación en Agricultura

PLASMODIUM

PATHOLOGY

GENETIC RESISTANCE

Citar Enlace permanente

Hernández Valladares, M. , Naessens, Jan , Nagda, S.M. , Musoke, A.J. , Rihet, P. , Ole-MoiYoi, O.K. , Iraqi, F.A. , [Comparison of pathology in susceptible A/J and resistant C57BL/6J mice after infection with different sub-strains of Plasmodium chabaudi] , Comparison of pathology in susceptible A/J and resistant C57BL/6J mice after infection with different sub-strains of Plasmodium chabaudi

Descubre y comparte nuestro conocimiento público

Resultados de búsqueda

Gene-expression profiling discriminates between cerebral malaria (CM) - susceptible mice and CM-resistant mice

Mapping of a new quantitative trait locus for resistance to malaria in mice by a comparative mapping approach with human chromosome 5q31-q33

TNF as a malaria candidate gene: Polymorphism-screening and family-based association analysis of mild malaria attack and parasitemia in Burkina Faso

Confirmation and dissection of QTL controlling resistance to malaria in mice

Comparison of pathology in susceptible A/J and resistant C57BL/6J mice after infection with different sub-strains of Plasmodium chabaudi