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Fucoidans are sulphated polysaccharides that can be obtained from brown seaweed and marine invertebrates. They have anti-cancer properties, through their targeting of several signaling pathways and molecular mechanisms within malignant cells. This review describes the chemical structure diversity...


Reyes, Maria ElenaRiquelme, IsmaelSalvo, TomasZanella, LouiseLetelier, PabloBrebi, Priscilla[Brown Seaweed Fucoidan in Cancer: Implications in Metastasis and Drug Resistance]Brown Seaweed Fucoidan in Cancer: Implications in Metastasis and Drug Resistance

Gastric cancer is the third leading cause of cancer mortality worldwide. Unfortunately, most gastric cancer cases are diagnosed in an advanced, non-curable stage and with a limited response to chemotherapy. Drug resistance is one of the most important causes of therapy failure in gastric cancer p...


Riquelme, IsmaelLetelier, PabloRiffo Campos, Angela L.Brebi, PriscillaCarlos Roa, Juan[Emerging Role of miRNAs in the Drug Resistance of Gastric Cancer]Emerging Role of miRNAs in the Drug Resistance of Gastric Cancer

Biliary tract cancers (BTCs) are a group of highly aggressive malignant tumors with a poor prognosis. The current diagnosis is based mainly on imaging and intraoperative exploration due to brush cytology having a low sensitivity and the standard markers, such as carcinoembryonic antigen (CEA) and...


Letelier, PabloRiquelme, IsmaelHernández Monsalves, AlfonsoGuzman Oyarzo, NeftaliFarias, Jorge G.Carlos Roa, Juan[Circulating MicroRNAs as Biomarkers in Biliary Tract Cancers]Circulating MicroRNAs as Biomarkers in Biliary Tract Cancers

COVID-19 is an infectious disease caused by the SARS-CoV-2 virus, which has given rise to a global sanitary emergency. The clinical characteristics of COVID-19 are varied and can range from an asymptomatic infection to a mild to severe pneumonia. Recent studies have shown that different laborator...


Letelier, PabloEncina, NicoleMorales, PabloRiffo, AlejandraSilva, HalettRiquelme, IsmaelGuzman Oyarzo, Neftali[ROLE OF BIOCHEMICAL MARKERS IN THE MONITORING OF COVID-19 PATIENTS]ROLE OF BIOCHEMICAL MARKERS IN THE MONITORING OF COVID-19 PATIENTS

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