Fucoidans are sulphated polysaccharides that can be obtained from brown seaweed and marine invertebrates. They have anti-cancer properties, through their targeting of several signaling pathways and molecular mechanisms within malignant cells. This review describes the chemical structure diversity...
Reyes, Maria Elena
,
Riquelme, Ismael
,
Salvo, Tomas
,
Zanella, Louise
,
Letelier, Pablo
,
Brebi, Priscilla
,
[Brown Seaweed Fucoidan in Cancer: Implications in Metastasis and Drug Resistance]
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Brown Seaweed Fucoidan in Cancer: Implications in Metastasis and Drug Resistance
Gastric cancer is the third leading cause of cancer mortality worldwide. Unfortunately, most gastric cancer cases are diagnosed in an advanced, non-curable stage and with a limited response to chemotherapy. Drug resistance is one of the most important causes of therapy failure in gastric cancer p...
Riquelme, Ismael
,
Letelier, Pablo
,
Riffo Campos, Angela L.
,
Brebi, Priscilla
,
Carlos Roa, Juan
,
[Emerging Role of miRNAs in the Drug Resistance of Gastric Cancer]
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Emerging Role of miRNAs in the Drug Resistance of Gastric Cancer
Biliary tract cancers (BTCs) are a group of highly aggressive malignant tumors with a poor prognosis. The current diagnosis is based mainly on imaging and intraoperative exploration due to brush cytology having a low sensitivity and the standard markers, such as carcinoembryonic antigen (CEA) and...
Letelier, Pablo
,
Riquelme, Ismael
,
Hernández Monsalves, Alfonso
,
Guzman Oyarzo, Neftali
,
Farias, Jorge G.
,
Carlos Roa, Juan
,
[Circulating MicroRNAs as Biomarkers in Biliary Tract Cancers]
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Circulating MicroRNAs as Biomarkers in Biliary Tract Cancers
COVID-19 is an infectious disease caused by the SARS-CoV-2 virus, which has given rise to a global sanitary emergency. The clinical characteristics of COVID-19 are varied and can range from an asymptomatic infection to a mild to severe pneumonia. Recent studies have shown that different laborator...
Letelier, Pablo
,
Encina, Nicole
,
Morales, Pablo
,
Riffo, Alejandra
,
Silva, Halett
,
Riquelme, Ismael
,
Guzman Oyarzo, Neftali
,
[ROLE OF BIOCHEMICAL MARKERS IN THE MONITORING OF COVID-19 PATIENTS]
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ROLE OF BIOCHEMICAL MARKERS IN THE MONITORING OF COVID-19 PATIENTS