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Previous studies in rats have demonstrated that chronic restraint stress triggers anhedonia, depressive-like behaviors, anxiety and a reduction in dendritic spine density in hippocampal neurons. In this study, we compared the effect of repeated stress on the expression of α-amino-3-hydroxy-5-meth...


Pacheco, A.Aguayo, F.I.Aliaga, E.Muñoz, M.García-Rojo, G.Olave, F.A.Parra-Fiedler, N.A.García-Pérez, A.Tejos-Bravo, M.Rojas, P.S.Parra, C.S.Fiedler, J.L.[Chronic Stress Triggers Expression of Immediate Early Genes and Differentially Affects the Expression of AMPA and NMDA Subunits in Dorsal and Ventral Hippocampus of Rats]Chronic Stress Triggers Expression of Immediate Early Genes and Differentially Affects the Expression of AMPA and NMDA Subunits in Dorsal and Ventral Hippocampus of Rats

Studies conducted in rodents subjected to chronic stress and some observations in humans after psychosocial stress, have allowed to establish a link between stress and the susceptibility to many complex diseases, including mood disorders. The studies in rodents have revealed that chronic exposure...


Muñoz-Llanos, M.García-Pérez, M.A.Xu, X.Tejos-Bravo, M.Vidal, E.A.Moyano, T.C.Gutiérrez, R.A.Aguayo, F.I.Pacheco, A.García-Rojo, G.Aliaga, E.Rojas, P.S.Cidlowski, J.A.[MicroRNA Profiling and Bioinformatics Target Analysis in Dorsal Hippocampus of Chronically Stressed Rats: Relevance to Depression Pathophysiology]MicroRNA Profiling and Bioinformatics Target Analysis in Dorsal Hippocampus of Chronically Stressed Rats: Relevance to Depression Pathophysiology

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