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Objective Aflatoxin is known to cross the placental barrier and exposures in utero could influence genomic programming, foetal growth and development, resulting in long-term health effects. We aimed to determine aflatoxin exposure in Gambian women at two stages of pregnancy and during the rainy a...


Castelino, J.M.Domínguez Salas, PaulaRoutledge, M.N.Prentice, A.M.Moore, S.E.Hennig, B.J.Wild, C.P.Gong, Y.Y.[Seasonal and gestation-stage associated differences in aflatoxin exposure in pregnant Gambian women]Seasonal and gestation-stage associated differences in aflatoxin exposure in pregnant Gambian women

The aim of the study was to determine the geographical and seasonal variations in aflatoxin dietary exposure levels in adults from Senegal. A total of 168 adults (50% male) were recruited from three districts: Nioro du Rip (n=90), located in the Sudan Savannah agro-ecological zone where rainfall ...


Watson, S.Diedhiou, P.M.Atehnkeng, J.Dem, A.Bandyopadhyay, RanajitSrey, C.Routledge, M.N.Gong, Y.Y.[Seasonal and geographical differences in aflatoxin exposures in Senegal]Seasonal and geographical differences in aflatoxin exposures in Senegal

Background Interindividual epigenetic variation that occurs systemically must be established prior to gastrulation in the very early embryo and, because it is systemic, can be assessed in easily biopsiable tissues. We employ two independent genome-wide approaches to search for such variants. Res...


Silver, M.J.Kessler, N.J.Hennig, B.J.Domínguez Salas, PaulaLaritsky, E.Baker, M.S.Coarfa, C.Hernández Vargas, H.Castelino, J.M.Routledge, M.N.Yun Yun GongHerceg, Z.Yong Sun LeeKwanbok LeeMoore, S.E.Fulford, A.J.Prentice, A.M.Waterland, R.A.[Independent genomewide screens identify the tumor suppressor VTRNA2-1 as a human epiallele responsive to periconceptional environment]Independent genomewide screens identify the tumor suppressor VTRNA2-1 as a human epiallele responsive to periconceptional environment

The aflatoxin (AF) albumin adduct is often used as a biomarker for aflatoxin exposure in humans. An ELISA method previously used for aflatoxin serum albumin in human blood was used to analyse bovine serum samples (n = 22) collected from dairy cattle during an aflatoxin mitigation study in Kenya. ...


Saltzmann, J.Xu, Y.Gong, Y.Y.Kersten, S.Danicke, S.Routledge, M.N.Lindahl, Johanna F.Kersten, S.Danicke, S.Routledge, M.N.[Preliminary study on the relationship between aflatoxin-bovine serum albumin adducts in blood and aflatoxin M1 levels in milk of dairy cows]Preliminary study on the relationship between aflatoxin-bovine serum albumin adducts in blood and aflatoxin M1 levels in milk of dairy cows

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