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Double-stranded RNA (dsRNA)-specific endonucleases belonging to RNase III classes 3 and 2 process dsRNA precursors to small interfering RNA (siRNA) or microRNA, respectively, thereby initiating and amplifying RNA silencing-based antiviral defense and gene regulation in eukaryotic cells. However, ...


Kreuze, J.F.Savenkov, E.I.Cuéllar, Wilmer J.Xiangdong LiValkonen, J.P.T.[Viral class 1 RNase III involved in suppression of RNA silencing.]Viral class 1 RNase III involved in suppression of RNA silencing.
Souza, J. deFuentes, S.Savenkov, E.I.Cuéllar, Wilmer J.Kreuze, J.F.[The complete nucleotide sequence of sweet potato C6 virus : a carlavirus lacking a cysteine-rich protein]The complete nucleotide sequence of sweet potato C6 virus : a carlavirus lacking a cysteine-rich protein

The evolutionary divergence of Potato mop-top virus (PMTV), a tri-partite, single-stranded RNA virus, is exceptionally low, based on the analysis of sequences obtained from isolates from Europe, Asia and North America. In general, RNA viruses exist as dynamic populations of closely related and re...


Kalyandurg, P.Gil, J.F.Lukhovitskaya, N.I.Flores, B.Muller, G.Chuquillanqui, C.Palomino, L.Monjane, A.Barker, I.Kreuze, J.F.Savenkov, E.I.[Molecular and pathobiological characterization of sixty one potato mop-top virus full-length cDNAs reveals great variability of the virus in the center of potato domestication, novel genotypes and evidence for recombination.]Molecular and pathobiological characterization of sixty one potato mop-top virus full-length cDNAs reveals great variability of the virus in the center of potato domestication, novel genotypes and evidence for recombination.

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