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Svitek, NicholasSaya, R.Awino, EliasGilbert, S.C.Poole, Elizabeth J.Nene, VishvanathSteinaa, Lucilla[Immunogenicity and protection of the Theileria parva CTL antigen Tp1, with or without a leader sequence, using HAd5/MVA prime-boost vaccination]Immunogenicity and protection of the Theileria parva CTL antigen Tp1, with or without a leader sequence, using HAd5/MVA prime-boost vaccination
Svitek, NicholasSaya, R.Awino, EliasMunyao, S.Njoroge, T.Gilbert, S.Nene, VishvanathSteinaa, Lucilla[Evaluating the Ad5/MVA antigen delivery systems]Evaluating the Ad5/MVA antigen delivery systems

East Coast fever (ECF) is a highly fatal lymphoproliferative disease of cattle caused by Theileria parva, a tick-borne intracellular apicomplexan parasite. Parasite antigens that are targets of protective cytotoxic T lymphocyte (CTL) responses are required to formulate a sub-unit vaccine against ...


Akoolo, L.Pelle, RogerSaya, R.Awino, EliasNyanjui, J.Taracha, E.L.N.Kanyari, P.Mwangi, D.M.Graham, S.P.[Evaluation of the recognition of Theileria parva vaccine candidate antigens by cytotoxic T lymphocytes from Zebu cattle]Evaluation of the recognition of Theileria parva vaccine candidate antigens by cytotoxic T lymphocytes from Zebu cattle
Svitek, NicholasSteinaa, LucillaSaya, R.Awino, EliasNielsen, MortenBuus, SorenNene, Vishvanath[The quest for the needle (antigen) in the haystack (pathogen): Immunoinformatics to the rescue]The quest for the needle (antigen) in the haystack (pathogen): Immunoinformatics to the rescue

The protozoan parasite Theileria parva causes a usually fatal disease in cattle, known as East Coast fever. Cattle can be vaccinated by injecting live parasites simultaneously with long acting oxytetracycline (the Infection and Treatment Method, ITM). The immunity induced by ITM is believed to be...


Steinaa, LucillaSaya, R.Awino, EliasToye, Philip G.[Cytotoxic T lymphocytes from cattle immunized against Theileria parva exhibit pronounced cross-reactivity among different strain-specific epitopes of the Tp1 antigen]Cytotoxic T lymphocytes from cattle immunized against Theileria parva exhibit pronounced cross-reactivity among different strain-specific epitopes of the Tp1 antigen

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