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Contagious caprine pleuropneumonia (CCPP), caused by Mycoplasma capricolum subsp. capripneumoniae is a severe disease widespread in Africa and Asia. Limited knowledge is available on the pathogenesis of this organism, mainly due to the lack of a robust in vivo challenge model and the means to do ...


Liljander, Anne M.Sacchini, F.Stoffel, M.H.Schieck, Elise G.Stokar-Regenscheit, N.Labroussaa, F.Heller, M.Salt, J.Frey, J.Falquet, L.Goovaerts, D.Jores, Joerg[Reproduction of contagious caprine pleuropneumonia reveals the ability of convalescent sera to reduce hydrogen peroxide production in vitro]Reproduction of contagious caprine pleuropneumonia reveals the ability of convalescent sera to reduce hydrogen peroxide production in vitro

Mycoplasma mycoides subsp. mycoides is the etiologic agent of contagious bovine pleuropneumonia. We report here the complete genome sequence of the strain T1/44, which is widely used as a live vaccine in Africa.


Gourgues, G.Barre, A.Beaudoing, E.Weber, J.Magdelenat, G.Barbe, V.Schieck, Elise G.Jores, JoergVashee, S.Blanchard, AlainLartigue, C.Sirand-Pugnet, P.[Complete genome sequence of Mycoplasma mycoides subsp. mycoides T1/44, a vaccine strain against contagious bovine pleuropneumonia]Complete genome sequence of Mycoplasma mycoides subsp. mycoides T1/44, a vaccine strain against contagious bovine pleuropneumonia
Jores, JoergSchieck, Elise G.Liljander, Anne M.Sacchini, FlavioPosthaus, H.Lartigue, C.Blanchard, AlainLabroussaa, F.Vashee, S.[In vivo role of capsular polysaccharide in Mycoplasma mycoides]In vivo role of capsular polysaccharide in Mycoplasma mycoides

Contagious caprine pleuropneumonia (CCPP) caused by Mycoplasma capricolum subsp. capripneumoniae is a severe epidemic affecting mainly domestic Caprinae species but also affects wild Caprinae species. M. capricolum subsp. capripneumoniae belongs to the “Mycoplasma mycoides cluster.” The disease f...


Falquet, LaurentLiljander, Anne M.Schieck, Elise G.Gluecks, Ilona V.Frey, J.Jores, Joerg[Complete genome sequences of virulent Mycoplasma capricolum subsp. capripneumoniae strains F38 and ILRI181]Complete genome sequences of virulent Mycoplasma capricolum subsp. capripneumoniae strains F38 and ILRI181

Mycoplasma mycoides subsp. capri (Mmc) and subsp. mycoides (Mmm) are important ruminant pathogens worldwide causing diseases such as pleuropneumonia, mastitis and septicaemia. They express galactofuranose residues on their surface, but their role in pathogenesis has not yet been determined. The M...


Schieck, Elise G.Lartigue, C.Frey, J.Vozza, N.Hegermann, J.Miller, R.A.Valguarnera, E.Muriuki, C.Meens, J.Nene, VishvanathNaessens, JanWeber, J.Lowary, T.L.Vashee, S.Feldman, M.F.Jores, Joerg[Galactofuranose in Mycoplasma mycoides is important for membrane integrity and conceals adhesins but does not contribute to serum resistance]Galactofuranose in Mycoplasma mycoides is important for membrane integrity and conceals adhesins but does not contribute to serum resistance

Members of the Mycoplasma mycoides cluster’ represent important livestock pathogens worldwide. Mycoplasma mycoidessubsp. mycoides is the etiologic agent of contagious bovine pleuropneumonia (CBPP), which is still endemic in many parts of Africa. We report the genome sequences and annotation of tw...


Fischer, A.Santana-Cruz, I.Hegerman, J.Gourle, H.Schieck, Elise G.Lambert, M.Nadendla, S.Wesonga, H.O.Miller, R.A.Vashee, S.Weber, J.Meens, J.Frey, J.Jores, Joerg[High quality draft genomes of the Mycoplasma mycoides subsp.mycoides challenge strains Afadé and B237]High quality draft genomes of the Mycoplasma mycoides subsp.mycoides challenge strains Afadé and B237

Mycoplasmas are the smallest free-living organisms and cause a number of economically important diseases affecting humans, animals, insects, and plants. Here, we demonstrate that highly virulent Mycoplasma mycoides subspecies capri (Mmc) can be fully attenuated via targeted deletion of non-essent...


Jores, JoergMa, L.Ssajjakambwe, PaulSchieck, Elise G.Liljander, Anne M.Chandran, S.Stoffel, M.H.Cippa, V.Arfi, Y.Assad-Garcia, N.Falquet, L.Sirand-Pugnet, P.Blanchard, AlainLartigue, C.Posthaus, H.Labroussaa, F.Vashee, S.[Removal of a subset of non-essential genes fully attenuates a highly virulent Mycoplasma strain]Removal of a subset of non-essential genes fully attenuates a highly virulent Mycoplasma strain

Mycoplasma species are responsible for several economically significant livestock diseases for which there is a need for new and improved vaccines. Most of the existing mycoplasma vaccines are attenuated strains that have been empirically obtained by serial passages or by chemical mutagenesis. Th...


Lartigue, C.Valverde Timana, Y.Labroussaa, F.Schieck, Elise G.Liljander, Anne M.Sacchini, FlavioPosthaus, H.Batailler, B.Sirand-Pugnet, P.Vashee, S.Jores, JoergBlanchard, Alain[Attenuation of a pathogenic Mycoplasma strain by modification of the obg gene by using synthetic biology approaches]Attenuation of a pathogenic Mycoplasma strain by modification of the obg gene by using synthetic biology approaches

Members of ‘Mycoplasma mycoides cluster’ are important ruminant pathogens in Africa. Diseases caused by these Mycoplasma negatively affect the agricultural sector especially in developing countries through losses in livestock productivity, mortality and international trade restrictions. There is ...


Kama-Kama, F.Midiwo, JacobNg'ang'a, J.Maina, N.Schieck, Elise G.Omosa, L.K.Osanjo, G.Naessens, Jan[Selected Ethno-medicinal plants from Kenya with in vitroactivity against major African livestock pathogens belonging to the “Mycoplasma mycoides cluster’]Selected Ethno-medicinal plants from Kenya with in vitroactivity against major African livestock pathogens belonging to the “Mycoplasma mycoides cluster’

Mycoplasma mycoides subsp. mycoides (Mmm) is the causative agent of contagious bovine pleuropneumonia (CBPP), a severe pleuropneumonia in cattle. The abnormal accumulation of pleural fluid, called pleural effusion (PE), is one of the characteristics of this disease. We performed a proteomic analy...


Weldearegay, Yenehiwot BerhanuPich, AndreasSchieck, Elise G.Liljander, Anne M.Gicheru, N.Wesonga, H.O.Thiaucourt, FrancoisKiirika, L.M.Valentin-Weigand, PeterJores, JoergMeens, J.[Proteomic characterization of pleural effusion, a specific host niche of Mycoplasma mycoides subsp. mycoides from cattle with contagious bovine pleuropneumonia (CBPP)]Proteomic characterization of pleural effusion, a specific host niche of Mycoplasma mycoides subsp. mycoides from cattle with contagious bovine pleuropneumonia (CBPP)

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