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A preliminary search for QTLs in a cattle F2 resource populations segregating for trypanotolerance has revealed three large candidate chromosomal regions (Bta02, Bta05, Bta07). In order to narrow down the position of the trypanotolerant QTLs, we are building comparative chromosomal maps between c...


Nilsson, P.H.Kang'a, S.Rottengatter, K.Suedbeck, U.Iraqui, F.Mwakaya, J.Mwangi, D.Womack, J.E.Goldammer, T.Schwerin, M.Bradley, D.Agaba, MorrisSugimoto, K.Gelhaus, A.Horstmann, R.Teale, A.J.Kemp, Stephen J.Hanotte, Olivier H.[Radiation hybrid maps of candidate trypanotolerance regions in cattle]Radiation hybrid maps of candidate trypanotolerance regions in cattle

A two species comparative genome scanning approach has been taken to mapping, and eventually identifying, genes at quantitative trait loci (QTL) influencing resistance to trypanosomosis due to infection with Trypanosoma congolense. Using two large murine F2 and two F6 advanced intercross populati...


Teale, A.J.Agaba, MorrisClapcott, S.J.Gelhaus, A.Haley, C.Psifidis, A.Horstmann, R.Iraqui, F.Kemp, Stephen J.Nilsson, P.Schwerin, M.Sekikawa, K.Soller, M.Sugimoto, Y.Womack, J.[Resistance to trypanosomosis: Of markers, genes and mechanisms]Resistance to trypanosomosis: Of markers, genes and mechanisms
Kang'a, S.Nilsson, P.Goldammer, T.Mwakaya, J.Njagi, E.N.M.Schwerin, M.Hanotte, Olivier H.[Construction of a BAC contig at a cattle QTL region controlling resistance to trypanosomosis on BTA7 that is homologous to the murine T1R1 region on MMU17]Construction of a BAC contig at a cattle QTL region controlling resistance to trypanosomosis on BTA7 that is homologous to the murine T1R1 region on MMU17
Kang'a, S.Nilsson, P.Goldammer, T.Mwakaya, J.Elliot, J.S.Womack, J.E.Schwerin, M.Njagi, E.N.M.Hanotte, Olivier H.[From QTL to candidate genes - an example from QTL mapping for trypanosomiasis resistance in cattle. Abstract]From QTL to candidate genes - an example from QTL mapping for trypanosomiasis resistance in cattle. Abstract

Trypanosomiasis is one of the most important diseases in African cattle. About 3 million cattle die every year by this disease. However, about 5 percent of the total African cattle have a natural resistance against trypanosomiasis. In a preliminary study markers linked to trypanotolerance have be...


Goldammer, T.Brunner, R.M.Kang'a, S.Hanotte, Olivier H.Schwerin, M.[Generation of a bovine BAC pool for chromosome region BTA7q14-22 correlated to the trait trypanotolerance]Generation of a bovine BAC pool for chromosome region BTA7q14-22 correlated to the trait trypanotolerance

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