The main conclusion from the present study is that T. parva sporozoite entry is dependent on a functional host cell actin cytoskeleton and is not driven by the parasite. Treating lymphocytes with cytochalasin D resulted in a dose-dependent reduction in the levels of host cell infection. However, ...
Shaw, M.K.
,
[Theileria parva: Sporozoite entry into bovine lymphocytes is not dependent on the parasite cytoskeleton]
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Theileria parva: Sporozoite entry into bovine lymphocytes is not dependent on the parasite cytoskeleton
The role of calcium in Theileria parva sporozoite entry into bovine lymphocytes was examined. Depletion of Ca2+ from the external medium had little effect on sporozoite entry suggesting that the initial sporozoite-host cell interaction is a Ca2+-independent process. Sporozoite entry could, howeve...
Shaw, M.K.
,
[Mobilization of intrasporozoite Ca(2+) is essential for Theileria parva sporozoite invasion of bovine lymphocytes]
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Mobilization of intrasporozoite Ca(2+) is essential for Theileria parva sporozoite invasion of bovine lymphocytes
The entry of Theileria parva merozoites into bovine erythrocytes in vivo is described and compared to sporozoite invasion of lymphocytes. Merozoites make initial contact with erythrocytes with any part of their surface and invasion of the host cell does not require the reorientation of the apical...
Shaw, M.K.
,
Tilney, L.G.
,
[The entry of Theileria parva merozoites into bovine erythrocytes occurs by a process similar to sporozoite invasion of lymphocytes]
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The entry of Theileria parva merozoites into bovine erythrocytes occurs by a process similar to sporozoite invasion of lymphocytes