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Conditions were established to obtain depletion of T lymphocyte subsets in lymphoid tissues of calves by injection of mouse monoclonal antibodies to T cell antigens. Adverse reactions were avoided by injecting small quantities of antibody until target cells had disappeared from blood. Two differe...


Naessens, JanScheerlinck, J.P.Buysscher, E.V. deKennedy, D.Sileghem, M.R.[Effective in vivo depletion of T cell subpopulations and loss of memory cells in cattle using mouse monoclonal antibodies]Effective in vivo depletion of T cell subpopulations and loss of memory cells in cattle using mouse monoclonal antibodies
Naessens, JanSileghem, M.R.MacHugh, Niall D.Park, Y.H.Davis, W.C.Toye, Philip G.[Selection of BoCD25 monoclonal antibodies by screening mouse L cells transfected with the bovine p55-interleukin-2 (IL-2) receptor gene]Selection of BoCD25 monoclonal antibodies by screening mouse L cells transfected with the bovine p55-interleukin-2 (IL-2) receptor gene
Sileghem, M.R.Saya, R.Ellis, J.Flynn, J.N.Peel, J.E.Williams, D.J.L.[Detection and neutralization of bovine tumor necrosis factor by a monoclonal antibody]Detection and neutralization of bovine tumor necrosis factor by a monoclonal antibody

This paper determines whether tumour necrosis factor (TNF alpha) (a cytokine that is predominantly secreted by cells of the monocyte/macrophage lineage) production is induced during bovine trypanosomiasis and wheather or not production is correlated with disease. TNF alpha titres in plasma from B...


Sileghem, M.R.Gaidulis, L.[Production of tumour necrosis factor alpha during bovine trypanosomiasis: possible correlation with severity of anaemia associated with the disease]Production of tumour necrosis factor alpha during bovine trypanosomiasis: possible correlation with severity of anaemia associated with the disease

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