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Sileghem, M.R.Flynn, J.N.Logan-Henfrey, L.L.Ellis, J.[Tumour necrosis factor production by monocytes from cattle infected with Trypanosoma (Duttonella) vivax and Trypanosoma (Nannomonas) congolense STI possible association with severity of anaemia associated with the disease]Tumour necrosis factor production by monocytes from cattle infected with Trypanosoma (Duttonella) vivax and Trypanosoma (Nannomonas) congolense STI possible association with severity of anaemia associated with the disease
Darji, A.Sileghem, M.R.Heremans, H.Brys, L.Baetselier, P. de[Inhibition of T-cell responsiveness during experimental infections with Trypanosoma brucei: Active involvement of endogenous gamma interferon]Inhibition of T-cell responsiveness during experimental infections with Trypanosoma brucei: Active involvement of endogenous gamma interferon
Flynn, J.N.Sileghem, M.R.[The role of the macrophage in induction of immunosuppression in Trypanosoma congolense-infected cattle]The role of the macrophage in induction of immunosuppression in Trypanosoma congolense-infected cattle
Flynn, J.N.Sileghem, M.R.Williams, D.J.L.[Parasite-specific T-Cell response of trypanotolerant and trypanosusceptible cattle during infection with Trypanosoma congolense]Parasite-specific T-Cell response of trypanotolerant and trypanosusceptible cattle during infection with Trypanosoma congolense

Mycoplasma strains being considered as pathogenic or non-pathogenic for cattle were tested on their capacity to activate bovine alveolar macrophages in vitro. Of particular interest was the behaviour of Mycoplasma mycoides ssp. mycoides small colony type (M.m.m. SC), the causative agent of contag...


Jungi, T.W.Krampe, M.Sileghem, M.R.Griot, C.Nicolet, J.[Differential and strain-specific triggering of bovine alveolar macrophage effector functions by mycoplasmas]Differential and strain-specific triggering of bovine alveolar macrophage effector functions by mycoplasmas
Darji, A.Lucas, R.Magez, S.Torreele, E.Palacios, J.Sileghem, M.R.Bajyana Songa, E.Hamers, R.Baetselier, P. de[Mechanisms underlying trypanosome-elicited immunosuppression]Mechanisms underlying trypanosome-elicited immunosuppression

Immune mechanisms against Cowdria ruminantium infection in livestock hosts are being investigated. This knowledge will be important for identification of protective antigens of C. ruminantium which will have application in the Development of vaccines against heartwater. T-cell Con-A supernatants ...


Mahan, S.M.Sileghem, M.R.Smith, G.Byrom, B.[Role of interferon gamma in control of Cowdria ruminantium growth in-vitro. Abstract]Role of interferon gamma in control of Cowdria ruminantium growth in-vitro. Abstract
Sileghem, M.R.Flynn, J.N.[Suppression of T-cell responsiveness during tsetse-transmitted trypanosomiasis in cattle]Suppression of T-cell responsiveness during tsetse-transmitted trypanosomiasis in cattle

In previous studies, the resistance to infection by Trypanosoma congolense has been localized in a region of chromosome 17 consisting the gene of TNF alpha. On the other hand, it has been Reported that the TNF alpha has a trypanolitic activity. So, we have started to study the expression of TN al...


Iraqi, F.A.Sileghem, M.R.Teale, A.J.[TNF-alpha expression in trypanosomiasis resistant and susceptible mouse strains during infection with Trypanosoma congolense]TNF-alpha expression in trypanosomiasis resistant and susceptible mouse strains during infection with Trypanosoma congolense

This paper determines whether tumour necrosis factor (TNF alpha) (a cytokine that is predominantly secreted by cells of the monocyte/macrophage lineage) production is induced during bovine trypanosomiasis and wheather or not production is correlated with disease. TNF alpha titres in plasma from B...


Sileghem, M.R.Gaidulis, L.[Production of tumour necrosis factor alpha during bovine trypanosomiasis: possible correlation with severity of anaemia associated with the disease]Production of tumour necrosis factor alpha during bovine trypanosomiasis: possible correlation with severity of anaemia associated with the disease

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