Natural resistance to African trypanosomiasis in certain Bos taurus cattle in West Africa, called trypanotolerance, may hold solutions for control of this economically crippling disease. Comparison of immune responses between trypanotolerant and trypanosusceptible cattle have shown some differen...
Naessens, Jan
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Teale, A.J.
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Sileghem, M.R.
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[Identification of mechanisms of natural resistance to African trypanosomiasis in cattle]
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Identification of mechanisms of natural resistance to African trypanosomiasis in cattle
Naessens, Jan
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Grab, D.J.
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Sileghem, M.R.
,
[Identifying the mechanisms of trypanotolerance in cattle]
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Identifying the mechanisms of trypanotolerance in cattle
Mice infected with African trypanosomes produce exceptionally large amounts of serum IgM, a major part of which binds to non-trypanosome antigens such as trinitrophenol and single-strand DNA. In this paper, we describe that in cattle infected with Trypanosoma congolense and T. vivax, similar anti...
Buza, J.J.
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Sileghem, M.R.
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Gwakisa, P.S.
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Naessens, Jan
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[CD5+B lymphocytes are the main source of antibodies reactive with non-parasite antigens in Trypanosoma congolense infected cattle]
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CD5+B lymphocytes are the main source of antibodies reactive with non-parasite antigens in Trypanosoma congolense infected cattle
Immune mechanisms against Cowdria ruminantium infection in livestock hosts are being investigated. This knowledge will be important for identification of protective antigens of C. ruminantium which will have application in the Development of vaccines against heartwater. T-cell Con-A supernatants ...
Mahan, S.M.
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Sileghem, M.R.
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Smith, G.
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Byrom, B.
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[Role of interferon gamma in control of Cowdria ruminantium growth in-vitro. Abstract]
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Role of interferon gamma in control of Cowdria ruminantium growth in-vitro. Abstract