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Ellis, J.A.Fish, W.R.Sileghem, M.R.McOdimba, F.A.[A calorimetric assay for trypanosome viability and metabolic function]A calorimetric assay for trypanosome viability and metabolic function

The membrane-associated form of the variable surface glycoprotein (mfVSG) from African trypanosomes is a potent macrophage activator capable of inducing production of tumor necrosis factor z (TNFalfa) in both bovine and murine models. Using a bovine model. we have re-investigated the hypothesis t...


Sileghem, M.R.Saya, R.Grab, D.J.Naessens, Jan[An accessory role for the diacylglycerol moiety of variable surface glycoprotein of African trypanosomes in the simulation of bovine monocytes]An accessory role for the diacylglycerol moiety of variable surface glycoprotein of African trypanosomes in the simulation of bovine monocytes

Experimental infections of mice with the African trypanosome Trypanosoma brucei lead to a profound state of T-cell unresponsiveness in the lymph node cell (LNC) compartment. This suppression is mediated by macrophage-like cells which inhibit interleukin 2 (IL-2) secretion and down-regulate IL-2 r...


Darji, A.Beschin, A.Sileghem, M.R.Heremans, H.Brys, L.Baetselier, P. de[In vitro simulation of immuno-suppression caused by Trypanosoma brucei: Active involvement of gamma interferon and tumor necrosis factor in the pathway of suppression]In vitro simulation of immuno-suppression caused by Trypanosoma brucei: Active involvement of gamma interferon and tumor necrosis factor in the pathway of suppression
Darji, A.Sileghem, M.R.Heremans, H.Brys, L.Baetselier, P. de[Inhibition of T-cell responsiveness during experimental infections with Trypanosoma brucei: Active involvement of endogenous gamma interferon]Inhibition of T-cell responsiveness during experimental infections with Trypanosoma brucei: Active involvement of endogenous gamma interferon

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