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Cho-Ngwa, F.Assam-Assam, J.P.Ane-Anyangwe, I.Skilton, Robert A.Pelle, RogerKitavi, M.Nzuki, I.Nyonka, J.Tedom, J.C.Beng, V.P.Akoachere, Jane-FrancisNjie, M.Titanji, V.P.K.[Molecular and phenotypic characterisation of mycobacterium tuberculosis complex]Molecular and phenotypic characterisation of mycobacterium tuberculosis complex

Harvey, Jagger J.W.Djikeng, AppolinaireSkilton, Robert A.[BecA hub research, facilities, and capacity building]BecA hub research, facilities, and capacity building
Bishop, Richard P.Musoke, A.J.Skilton, Robert A.Morzaria, S.P.Gardner, M.Nene, Vishvanath[Theileria: Life cycle stages associated with the ixodid tick vector]Theileria: Life cycle stages associated with the ixodid tick vector
Bishop, Richard P.Musoke, A.J.Skilton, Robert A.Odongo, D.Scoles, Glen A.Knowles, D.Nene, Vishvanath[Approaches to improved understanding of vector parasite interaction within the genus Theileria and their Ixodid tick vectors]Approaches to improved understanding of vector parasite interaction within the genus Theileria and their Ixodid tick vectors

Theileria are tick-transmitted, haemoprotozoan parasites infecting wild and domestic ungulates throughout many areas of the world. The most economically important species are T. parva and T. annulata which are pathogenic to cattle, and T. lestoquardi (syn hirci) which is pathogenic to sheep and g...


Skilton, Robert A.Musoke, A.J.Nene, VishvanathWasawo, D.P.S.Wells, C.W.Spooner, P.R.Bishop, Richard P.Osaso, J.Nkonge, C.Latif, A.Morzaria, S.P.[Molecular characterisation of a Theileria lestoquardi gene encoding a candidate sporozoite vaccine antigen]Molecular characterisation of a Theileria lestoquardi gene encoding a candidate sporozoite vaccine antigen

Field and experimental bovine infection sera were used in immunoblots of sporozoite and schizont lysates of Theileria parva to identify candidate diagnostic antigens. Four parasite antigens of Mr 67,000 (p67), 85,000 (the polymorphic immunodominant molecule, PIM), 104,000 (p104), and 150,000 (p15...


Katende, J.Morzaria, S.P.Toye, Philip G.Skilton, Robert A.Nene, VishvanathNkonge, C.Musoke, A.J.[An enzyme-linked immunosorbent assay for detection of Theileria parva antibodies in cattle using a recombinant polymorphic immunodominant molecule]An enzyme-linked immunosorbent assay for detection of Theileria parva antibodies in cattle using a recombinant polymorphic immunodominant molecule

The 'Muguga cocktail' which is composed of three Theileria parva stocks Muguga. Kiambu 5 and Serengeti-transformed has been used extensively for live vaccination against East Coast fever in cattle in eastern, central and southern Africa. Herein we describe the molecular characterization of the T....


Bishop, Richard P.Geysen, D.Spooner, P.R.Skilton, Robert A.Nene, VishvanathDolan, T.T.Morzaria, S.P.[Molecular and immunological characterisation of Theileria parva stocks which are components of the Muguga cocktail used for vaccination against East Coast fever in cattle]Molecular and immunological characterisation of Theileria parva stocks which are components of the Muguga cocktail used for vaccination against East Coast fever in cattle

Ixodid ticks manipulate mammalian host pathways by secreting molecules from salivary glands. Novel cDNAs containing functional secretion signals were isolated from ixodid tick salivary glands using a signal sequence trap. Only 15/61 Rhipicephalus appendiculatus and 1/7 Amblyomma variegatum cDNAs ...


Lambson, B.Nene, VishvanathObura, M.Shah, TushaarPandit, P.Ole-MoiYoi, O.K.Delroux, K.Welburn, S.C.Skilton, Robert A.Villiers, Etienne P. deBishop, Richard P.[Identification of candidate sialome components expressed in ixodid tick salivary glands using secretion signal complementation in mammalian cells]Identification of candidate sialome components expressed in ixodid tick salivary glands using secretion signal complementation in mammalian cells

A cross-sectional survey was carried out in four counties of Jonglei State, South Sudan, between May and June 2012 to determine the distribution and northern limit of Theileria parva, the causative agent of East Coast fever in cattle, and its tick vector Rhipicephalus appendiculatus, as a prerequ...


Marcellino, Wani L.Salih, Diaeldin A.Njahira, Moses N.Ndiwa, Nicholas N.Araba, A.El Hussein, A.M.Seitzer, U.Ahmed, J.S.Bishop, Richard P.Skilton, Robert A.[The Emergence of Theileria parva in Jonglei State, South Sudan: Confirmation using molecular and serological diagnostic tools]The Emergence of Theileria parva in Jonglei State, South Sudan: Confirmation using molecular and serological diagnostic tools

Commercial vaccines based on recombinant forms of the Bm86 tick gut antigen are used to control the southern cattle tick, Rhipicephalus microplus, a 1-host species, in Australia and Latin America. We describe herein sequence polymorphism in genes encoding Ra86 homologues of Bm86 in the brown ear ...


Kamau, L.M.Skilton, Robert A.Githaka, Naftaly W.Kiara, Henry K.Kabiru, E.Shah, TushaarMusoke, A.J.Bishop, Richard P.[Extensive polymorphism of Ra86 genes in field populations of Rhipicephalus appendiculatus from Kenya]Extensive polymorphism of Ra86 genes in field populations of Rhipicephalus appendiculatus from Kenya

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