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Morzaria, S.P.Young, J.R.Spooner, P.R.Dolan, T.T.Bishop, Richard P.[Theileria parva: a restriction map and genetic recombination]Theileria parva: a restriction map and genetic recombination
Bishop, Richard P.Spooner, P.R.Kanhai, G.Latif, A.Hove, T.Dolan, T.T.[Molecular characterization of theileria parasites. Application to the epidemiology of theileriosis in Zimbabwe]Molecular characterization of theileria parasites. Application to the epidemiology of theileriosis in Zimbabwe

The 'Muguga cocktail' which is composed of three Theileria parva stocks Muguga. Kiambu 5 and Serengeti-transformed has been used extensively for live vaccination against East Coast fever in cattle in eastern, central and southern Africa. Herein we describe the molecular characterization of the T....


Bishop, Richard P.Geysen, D.Spooner, P.R.Skilton, Robert A.Nene, VishvanathDolan, T.T.Morzaria, S.P.[Molecular and immunological characterisation of Theileria parva stocks which are components of the Muguga cocktail used for vaccination against East Coast fever in cattle]Molecular and immunological characterisation of Theileria parva stocks which are components of the Muguga cocktail used for vaccination against East Coast fever in cattle

Two recombinant vaccines against Theileria parva, based on a near full-length version of the sporozoite surface antigen p67 (p67635), or an 80 amino acid C-terminal section (p67C), were evaluated by exposure of immunized cattle to natural tick challenge in two sites at the Kenya Coast and one i...


Musoke, A.J.Rowlands, G.J.Nene, VishvanathNyanjui, J.Katende, J.Spooner, P.R.Mwaura, S.Odongo, D.Nkonge, C.Mbogo, S.Bishop, Richard P.Morzaria, S.P.[Subunit vaccine based on the p67 major surface protein of Theileria parva sporozoites reduces severity of infection derived from field tick challenge]Subunit vaccine based on the p67 major surface protein of Theileria parva sporozoites reduces severity of infection derived from field tick challenge
Morzaria, S.P.Irvin, A.D.Taracha, E.A.Spooner, P.R.Voigt, W.P.Fujinaga, T.Katende, J.M.[Immunization against East Coast fever. The use of selected stocks of Theileria parva for immunization of cattle exposed to field challenge]Immunization against East Coast fever. The use of selected stocks of Theileria parva for immunization of cattle exposed to field challenge
Morzaria, S.P.Spooner, P.R.Bishop, Richard P.Musoke, A.J.Young, J.R.[SfiI and NotI polymorphisms in theileria stocks detected by pulsed field gel electrophoresis]SfiI and NotI polymorphisms in theileria stocks detected by pulsed field gel electrophoresis

The preparation of Theileria parva stabilates has been described by Cunningham et al (1973). The method is detailed in the FAO report (1978) and the FAO tick and tick-borne Disease Manual (1984). Theileria parva stabilates are a source of viable sporozoites that can be used to immunise cattle by ...


Morzaria, S.P.Spooner, P.R.Bishop, Richard P.Mwaura, S.[The preparation of a composite stabilate for immunisation against East Coast fever]The preparation of a composite stabilate for immunisation against East Coast fever

The current Infection and Treatment Method of vaccination against East Coast fever comprises an inoculation of live Theileria parva sporozoites and simultaneous administration of oxytetracycline. Immunization with a combination of parasite types has been shown to provide broader protection than i...


Patel, EktaLubembe, D.M.Gachanja, J.Mwaura, S.Spooner, P.R.Toye, Philip G.[Molecular characterization of live Theileria parva sporozoite vaccine stabilates reveals extensive genotypic diversity]Molecular characterization of live Theileria parva sporozoite vaccine stabilates reveals extensive genotypic diversity

Partial nucleotide sequences of large subunit ribosomal RNA (LSU rRNA) coding genes of Theileria parva and T. taurotragi were determined. Alignment of the T. parva and T. taurotragi sequences revealed species-specific regions within the LSU rRNA genes. A major species variable region, located bet...


Bishop, Richard P.Allsopp, B.A.Spooner, P.R.Sohanpal, B.K.Morzaria, S.P.Gobright, E.I.[Theileria: Improved species discrimination using oligonucleotide derived from large subunit ribosomal RNA sequences]Theileria: Improved species discrimination using oligonucleotide derived from large subunit ribosomal RNA sequences
Irvin, A.D.Chumo, R.S.C.Dobbelaere, D.A.E.Goddeeris, B.M.Katende, J.Minami, T.Ocama, J.G.R.Spooner, P.R.[Preliminary studies on East Coast fever in the coast province of Kenya]Preliminary studies on East Coast fever in the coast province of Kenya

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