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Journal Article 2018-05-02

Autor: Steinaa, Lucilla Svitek, Nichiolas Awino, Elias Njoroge, Thomas Saya, Rosemary M. Toye, Philip G.

Background The tick-borne protozoan parasite Theileria parva causes a usually fatal cattle disease known as East Coast fever in sub-Saharan Africa, with devastating consequences for poor small-holder farmers. Immunity to T. parva, believed to be mediated by a cytotoxic T lymphocyte (CTL) response...

Enlace original: https://cgspace.cgiar.org/handle/10568/96893

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Steinaa, Lucilla ,  Svitek, Nichiolas ,  Awino, Elias ,  Njoroge, Thomas ,  Saya, Rosemary M. ,  Toye, Philip G. ,  [Immunization with one Theileria parva strain results in similar level of CTL strain-specificity and protection compared to immunization with the three-component Muguga cocktail in MHC-matched animals] ,  Immunization with one Theileria parva strain results in similar level of CTL strain-specificity and protection compared to immunization with the three-component Muguga cocktail in MHC-matched animals
Journal Article 2018-01-17

Autor: Steinaa, Lucilla Svitek, Nicholas Awino, Elias Saya, Rosemary Toye, Philip G.

Objectives: The objective of this study was to assess whether cytotoxic T cells (CTL) generated by the live vaccine, known as “ITM Muguga cocktail”, which is used for the cattle disease East Cost fever (ECF) in Sub-Saharan Africa, showed a broad reactivity against many different strains of the ca...

Enlace original: https://cgspace.cgiar.org/handle/10568/92437

Investigación en Agricultura
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Steinaa, Lucilla ,  Svitek, Nicholas ,  Awino, Elias ,  Saya, Rosemary ,  Toye, Philip G. ,  [Cytotoxic T lymphocytes from cattle sharing the same MHC class I haplotype and immunized with live Theileria parva sporozoites differ in antigenic specificity] ,  Cytotoxic T lymphocytes from cattle sharing the same MHC class I haplotype and immunized with live Theileria parva sporozoites differ in antigenic specificity
Poster 2016-05-22

Autor: Svitek, Nicholas Saya, R. Awino, Elias Gilbert, S.C. Poole, Elizabeth J. Nene, Vishvanath Steinaa, Lucilla
Enlace original: https://cgspace.cgiar.org/handle/10568/75989

Investigación en Agricultura
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Svitek, Nicholas ,  Saya, R. ,  Awino, Elias ,  Gilbert, S.C. ,  Poole, Elizabeth J. ,  Nene, Vishvanath ,  Steinaa, Lucilla ,  [Immunogenicity and protection of the Theileria parva CTL antigen Tp1, with or without a leader sequence, using HAd5/MVA prime-boost vaccination] ,  Immunogenicity and protection of the Theileria parva CTL antigen Tp1, with or without a leader sequence, using HAd5/MVA prime-boost vaccination
Presentation 2015-02-09

Autor: Svitek, Nicholas Saya, R. Awino, Elias Munyao, S. Njoroge, T. Gilbert, S. Nene, Vishvanath Steinaa, Lucilla
Enlace original: https://cgspace.cgiar.org/handle/10568/67415

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Svitek, Nicholas ,  Saya, R. ,  Awino, Elias ,  Munyao, S. ,  Njoroge, T. ,  Gilbert, S. ,  Nene, Vishvanath ,  Steinaa, Lucilla ,  [Evaluating the Ad5/MVA antigen delivery systems] ,  Evaluating the Ad5/MVA antigen delivery systems
Journal Article 2015-09-15

Autor: Svitek, Nicholas Awino, Elias Nene, Vishvanath Steinaa, Lucilla

We have recently shown that the BoLA-A18 variant haplotype (BoLA-6*01302) is more prevalent than the BoLA-A18 haplotype (BoLA-6*01301) in a sample of Holstein/Friesian cattle in Kenya. These MHC class I allelic variants differ by a single amino acid polymorphism (Glu97 to Leu97) in the peptide-bi...

Enlace original: https://cgspace.cgiar.org/handle/10568/67244

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Svitek, Nicholas ,  Awino, Elias ,  Nene, Vishvanath ,  Steinaa, Lucilla ,  [BoLA-6*01301 and BoLA-6*01302, two allelic variants of the A18 haplotype, present the same epitope from the Tp1 antigen of Theileria parva] ,  BoLA-6*01301 and BoLA-6*01302, two allelic variants of the A18 haplotype, present the same epitope from the Tp1 antigen of Theileria parva
Book Chapter 2016

Autor: Svitek, Nicholas Taracha, E.L.N. Saya, R. Awino, Elias Nene, Vishvanath Steinaa, Lucilla

Flow cytometry, enzyme-linked immunospot (ELISpot) and cellular cytotoxicity assays are powerful tools for studying the cellular immune response towards intracellular pathogens and vaccines in livestock species. Lymphocytes from immunized animals can be purified using Ficoll-Paque density gradien...

Enlace original: https://cgspace.cgiar.org/handle/10568/72681

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Svitek, Nicholas ,  Taracha, E.L.N. ,  Saya, R. ,  Awino, Elias ,  Nene, Vishvanath ,  Steinaa, Lucilla ,  [Analysis of the cellular immune responses to vaccines] ,  Analysis of the cellular immune responses to vaccines
Video 2014-02-03

Autor: Steinaa, Lucilla

An interview with Lucilla Steinaa of ILRI on the sidelines of an inception workshop for the Improved Vaccines of the Control of East Coast Fever in Cattle in Africa Project, held 27-29 Jan in Nairobi, Kenya.

Enlace original: https://cgspace.cgiar.org/handle/10568/34833

Investigación en Agricultura
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Steinaa, Lucilla ,  [Lucilla Steinaa: Improved Vaccines for the Control of East Coast Fever Inception Workshop] ,  Lucilla Steinaa: Improved Vaccines for the Control of East Coast Fever Inception Workshop
Brief 2018-04-30

Autor: Steinaa, Lucilla Henson, Sonal P. Buus, Soren Stryhn, Annette Nielsen, Morten Svitek, Nicholas Onzere, Cynthia K. Nyambego, Edwina B. Ndambuki, Gideon M. Bishop, Richard P.
Enlace original: https://cgspace.cgiar.org/handle/10568/92508

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Steinaa, Lucilla ,  Henson, Sonal P. ,  Buus, Soren ,  Stryhn, Annette ,  Nielsen, Morten ,  Svitek, Nicholas ,  Onzere, Cynthia K. ,  Nyambego, Edwina B. ,  Ndambuki, Gideon M. ,  Bishop, Richard P. ,  [Sequencing swine leucocyte alleles for vaccine development] ,  Sequencing swine leucocyte alleles for vaccine development

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