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Journal Article 2018-05-02

Autor: Steinaa, Lucilla Svitek, Nichiolas Awino, Elias Njoroge, Thomas Saya, Rosemary M. Toye, Philip G.

Background The tick-borne protozoan parasite Theileria parva causes a usually fatal cattle disease known as East Coast fever in sub-Saharan Africa, with devastating consequences for poor small-holder farmers. Immunity to T. parva, believed to be mediated by a cytotoxic T lymphocyte (CTL) response...

Enlace original: https://cgspace.cgiar.org/handle/10568/96893

Investigación en Agricultura
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Steinaa, Lucilla ,  Svitek, Nichiolas ,  Awino, Elias ,  Njoroge, Thomas ,  Saya, Rosemary M. ,  Toye, Philip G. ,  [Immunization with one Theileria parva strain results in similar level of CTL strain-specificity and protection compared to immunization with the three-component Muguga cocktail in MHC-matched animals] ,  Immunization with one Theileria parva strain results in similar level of CTL strain-specificity and protection compared to immunization with the three-component Muguga cocktail in MHC-matched animals
Journal Article 2018-01-17

Autor: Steinaa, Lucilla Svitek, Nicholas Awino, Elias Saya, Rosemary Toye, Philip G.

Objectives: The objective of this study was to assess whether cytotoxic T cells (CTL) generated by the live vaccine, known as “ITM Muguga cocktail”, which is used for the cattle disease East Cost fever (ECF) in Sub-Saharan Africa, showed a broad reactivity against many different strains of the ca...

Enlace original: https://cgspace.cgiar.org/handle/10568/92437

Investigación en Agricultura
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Steinaa, Lucilla ,  Svitek, Nicholas ,  Awino, Elias ,  Saya, Rosemary ,  Toye, Philip G. ,  [Cytotoxic T lymphocytes from cattle sharing the same MHC class I haplotype and immunized with live Theileria parva sporozoites differ in antigenic specificity] ,  Cytotoxic T lymphocytes from cattle sharing the same MHC class I haplotype and immunized with live Theileria parva sporozoites differ in antigenic specificity
Journal Article 2015-09-15

Autor: Svitek, Nicholas Awino, Elias Nene, Vishvanath Steinaa, Lucilla

We have recently shown that the BoLA-A18 variant haplotype (BoLA-6*01302) is more prevalent than the BoLA-A18 haplotype (BoLA-6*01301) in a sample of Holstein/Friesian cattle in Kenya. These MHC class I allelic variants differ by a single amino acid polymorphism (Glu97 to Leu97) in the peptide-bi...

Enlace original: https://cgspace.cgiar.org/handle/10568/67244

Investigación en Agricultura
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Svitek, Nicholas ,  Awino, Elias ,  Nene, Vishvanath ,  Steinaa, Lucilla ,  [BoLA-6*01301 and BoLA-6*01302, two allelic variants of the A18 haplotype, present the same epitope from the Tp1 antigen of Theileria parva] ,  BoLA-6*01301 and BoLA-6*01302, two allelic variants of the A18 haplotype, present the same epitope from the Tp1 antigen of Theileria parva

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