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Contagious caprine pleuropneumonia (CCPP), caused by Mycoplasma capricolum subsp. capripneumoniae is a severe disease widespread in Africa and Asia. Limited knowledge is available on the pathogenesis of this organism, mainly due to the lack of a robust in vivo challenge model and the means to do ...


Liljander, Anne M.Sacchini, F.Stoffel, M.H.Schieck, Elise G.Stokar-Regenscheit, N.Labroussaa, F.Heller, M.Salt, J.Frey, J.Falquet, L.Goovaerts, D.Jores, Joerg[Reproduction of contagious caprine pleuropneumonia reveals the ability of convalescent sera to reduce hydrogen peroxide production in vitro]Reproduction of contagious caprine pleuropneumonia reveals the ability of convalescent sera to reduce hydrogen peroxide production in vitro

Mycoplasmas are the smallest free-living organisms and cause a number of economically important diseases affecting humans, animals, insects, and plants. Here, we demonstrate that highly virulent Mycoplasma mycoides subspecies capri (Mmc) can be fully attenuated via targeted deletion of non-essent...


Jores, JoergMa, L.Ssajjakambwe, PaulSchieck, Elise G.Liljander, Anne M.Chandran, S.Stoffel, M.H.Cippa, V.Arfi, Y.Assad-Garcia, N.Falquet, L.Sirand-Pugnet, P.Blanchard, AlainLartigue, C.Posthaus, H.Labroussaa, F.Vashee, S.[Removal of a subset of non-essential genes fully attenuates a highly virulent Mycoplasma strain]Removal of a subset of non-essential genes fully attenuates a highly virulent Mycoplasma strain

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