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Foot-and-mouth disease (FMD) in Turkey is controlled using biannual mass vaccination of cattle. However, vaccine protection is undermined by population turnover and declining immunity. A dynamic model of the Turkish cattle population was created. Assuming biannual mass vaccination with a single-d...


Knight-Jones, T.J.D.Gubbins, S.Bulut, A.N.Stärk, K.D.C.Pfeiffer, Dirk U.Sumption, K.J.Paton, D.J.[Mass vaccination, immunity and coverage: modelling population protection against foot-and-mouth disease in Turkish cattle]Mass vaccination, immunity and coverage: modelling population protection against foot-and-mouth disease in Turkish cattle

Lyons, N.A.Knight-Jones, T.J.D.Bartels, C.Dulu, T.D.Stärk, K.D.C.Sumption, K.J.Fine, P.E.M.[Vaccine evaluation on large-scale dairy farms using routine prophylactic schedules for FMD]Vaccine evaluation on large-scale dairy farms using routine prophylactic schedules for FMD

Despite years of biannual mass vaccination of cattle, foot-and-mouth disease (FMD) remains uncontrolled in Anatolian Turkey. To evaluate protection after mass vaccination we measured post-vaccination antibodies in a cohort of cattle (serotypes O, A and Asia-1). To obtain results reflecting typica...


Knight-Jones, T.J.D.Bulut, A.N.Gubbins, S.Stark, K.D.C.Pfeiffer, Dirk U.Sumption, K.J.Paton, D.J.[Randomised field trial to evaluate serological response after foot-and-mouth disease vaccination in Turkey]Randomised field trial to evaluate serological response after foot-and-mouth disease vaccination in Turkey

We assessed research knowledge gaps in the fields of FMDV (foot-and-mouth disease virus) pathogenesis and molecular biology by performing a literature review (2011–15) and collecting research updates (2014) from 33 institutes from across the world. Findings were used to identify priority areas fo...


Robinson, L.Knight-Jones, T.J.D.Charleston, B.Rodríguez, L.L.Gay, C.G.Sumption, K.J.Vosloo, W.[Global foot-and-mouth disease research update and gap analysis: 7 – Pathogenesis and molecular biology]Global foot-and-mouth disease research update and gap analysis: 7 – Pathogenesis and molecular biology

This study assessed gaps and priorities for FMDV (foot-and-mouth disease virus) research in the field of immunology. The study took the form of a literature review (2011-15) combined with research updates collected in 2014 from 33 institutes from across the world. Findings were used to identify p...


Robinson, L.Knight-Jones, T.J.D.Charleston, B.Rodríguez, L.L.Gay, C.G.Sumption, K.J.Vosloo, W.[Global foot-and-mouth disease research update and gap analysis: 6 – Immunology]Global foot-and-mouth disease research update and gap analysis: 6 – Immunology

The Global Foot-and-mouth disease (FMD) Research Alliance periodically reviews the state of FMD research to assess progress and to identify new priorities. In this supplement we provide an update of global FMD research, comprising (i) this overview paper, which includes background information wit...


Knight-Jones, T.J.D.Robinson, L.Charleston, B.Rodríguez, L.L.Gay, C.G.Sumption, K.J.Vosloo, W.[Global foot-and-mouth disease research update and gap analysis: 1 – Overview of global status and research needs]Global foot-and-mouth disease research update and gap analysis: 1 – Overview of global status and research needs

We assessed knowledge gaps in foot-and-mouth disease (FMD) research. Findings are reported in a series of papers, and in this article, we consider biotherapeutics and disinfectants. The study took the form of a literature review (2011–2015) combined with research updates collected in 2014 from 33...


Robinson, L.Knight-Jones, T.J.D.Charleston, B.Rodríguez, L.L.Gay, C.G.Sumption, K.J.Vosloo, W.[Global foot-and-mouth disease research update and gap analysis: 5 – Biotherapeutics and disinfectants]Global foot-and-mouth disease research update and gap analysis: 5 – Biotherapeutics and disinfectants

This study assessed research knowledge gaps in the field of FMDV (foot-and-mouth disease virus) vaccines. The study took the form of a literature review (2011–15) combined with research updates collected in 2014 from 33 institutes from across the world. Findings were used to identify priority are...


Robinson, L.Knight-Jones, T.J.D.Charleston, B.Rodríguez, L.L.Gay, C.G.Sumption, K.J.Vosloo, W.[Global foot-and-mouth disease research update and gap analysis: 3 – Vaccines]Global foot-and-mouth disease research update and gap analysis: 3 – Vaccines

We assessed knowledge gaps in foot-and-mouth disease (FMD) research, and in this study, we consider (i) epidemiology, (ii) wildlife and (iii) economics. The study took the form of a literature review (2011–2015) combined with research updates collected in 2014 from 33 institutes from across the w...


Knight-Jones, T.J.D.Robinson, L.Charleston, B.Rodríguez, L.L.Gay, C.G.Sumption, K.J.Vosloo, W.[Global foot-and-mouth disease research update and gap analysis: 2 – Epidemiology, wildlife and economics]Global foot-and-mouth disease research update and gap analysis: 2 – Epidemiology, wildlife and economics

This study assessed knowledge gaps in foot-and-mouth disease (FMD) research in the field of diagnostics. The study took the form of a literature review (2011–15) combined with research updates collected in 2014 from 33 institutes from around the world. Findings were used to identify priority area...


Knight-Jones, T.J.D.Robinson, L.Charleston, B.Rodríguez, L.L.Gay, C.G.Sumption, K.J.Vosloo, W.[Global foot-and-mouth disease research update and gap analysis: 4 – Diagnostics]Global foot-and-mouth disease research update and gap analysis: 4 – Diagnostics

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