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Journal Article 2018-01-17

Autor: Steinaa, Lucilla Svitek, Nicholas Awino, Elias Saya, Rosemary Toye, Philip G.

Objectives: The objective of this study was to assess whether cytotoxic T cells (CTL) generated by the live vaccine, known as “ITM Muguga cocktail”, which is used for the cattle disease East Cost fever (ECF) in Sub-Saharan Africa, showed a broad reactivity against many different strains of the ca...

Enlace original: https://cgspace.cgiar.org/handle/10568/92437

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Steinaa, Lucilla ,  Svitek, Nicholas ,  Awino, Elias ,  Saya, Rosemary ,  Toye, Philip G. ,  [Cytotoxic T lymphocytes from cattle sharing the same MHC class I haplotype and immunized with live Theileria parva sporozoites differ in antigenic specificity] ,  Cytotoxic T lymphocytes from cattle sharing the same MHC class I haplotype and immunized with live Theileria parva sporozoites differ in antigenic specificity
Journal Article 2016-06-15

Autor: Nene, Vishvanath Kiara, Henry K. Lacasta, Anna Pelle, Roger Svitek, Nicholas Steinaa, Lucilla

Tremendous progress has been made over the last ten years on East Coast fever (ECF) research. Publication of a reference genome sequence of Theileria parva, the causative agent of ECF, has led to a more thorough characterization of the genotypic and antigenic diversity of the pathogen. It also fa...

Enlace original: https://cgspace.cgiar.org/handle/10568/72680

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Nene, Vishvanath ,  Kiara, Henry K. ,  Lacasta, Anna ,  Pelle, Roger ,  Svitek, Nicholas ,  Steinaa, Lucilla ,  [The biology of Theileria parva and control of East Coast fever—Current status and future trends] ,  The biology of Theileria parva and control of East Coast fever—Current status and future trends
Poster 2016-05-22

Autor: Svitek, Nicholas Saya, R. Awino, Elias Gilbert, S.C. Poole, Elizabeth J. Nene, Vishvanath Steinaa, Lucilla
Enlace original: https://cgspace.cgiar.org/handle/10568/75989

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Svitek, Nicholas ,  Saya, R. ,  Awino, Elias ,  Gilbert, S.C. ,  Poole, Elizabeth J. ,  Nene, Vishvanath ,  Steinaa, Lucilla ,  [Immunogenicity and protection of the Theileria parva CTL antigen Tp1, with or without a leader sequence, using HAd5/MVA prime-boost vaccination] ,  Immunogenicity and protection of the Theileria parva CTL antigen Tp1, with or without a leader sequence, using HAd5/MVA prime-boost vaccination
Presentation 2015-02-09

Autor: Svitek, Nicholas Saya, R. Awino, Elias Munyao, S. Njoroge, T. Gilbert, S. Nene, Vishvanath Steinaa, Lucilla
Enlace original: https://cgspace.cgiar.org/handle/10568/67415

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Svitek, Nicholas ,  Saya, R. ,  Awino, Elias ,  Munyao, S. ,  Njoroge, T. ,  Gilbert, S. ,  Nene, Vishvanath ,  Steinaa, Lucilla ,  [Evaluating the Ad5/MVA antigen delivery systems] ,  Evaluating the Ad5/MVA antigen delivery systems
Journal Article 2015-09-15

Autor: Svitek, Nicholas Awino, Elias Nene, Vishvanath Steinaa, Lucilla

We have recently shown that the BoLA-A18 variant haplotype (BoLA-6*01302) is more prevalent than the BoLA-A18 haplotype (BoLA-6*01301) in a sample of Holstein/Friesian cattle in Kenya. These MHC class I allelic variants differ by a single amino acid polymorphism (Glu97 to Leu97) in the peptide-bi...

Enlace original: https://cgspace.cgiar.org/handle/10568/67244

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Svitek, Nicholas ,  Awino, Elias ,  Nene, Vishvanath ,  Steinaa, Lucilla ,  [BoLA-6*01301 and BoLA-6*01302, two allelic variants of the A18 haplotype, present the same epitope from the Tp1 antigen of Theileria parva] ,  BoLA-6*01301 and BoLA-6*01302, two allelic variants of the A18 haplotype, present the same epitope from the Tp1 antigen of Theileria parva
Poster 2013-05-15

Autor: Awino, Elias Aye, R. Bertrand, S. Gesharisha, J. Gicheru, N. Jores, Joerg Liljander, Anne M. Muriuki, C. Naessens, Jan Nene, Vishvanath Njoroge, T. Nyongesa, S. Pelle, Roger Ssajjakambwe, P. Saya, R. Schieck, Elise G. Steinaa, Lucilla Svitek, Nicholas Wasilwa, J.
Enlace original: https://cgspace.cgiar.org/handle/10568/29063

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Awino, Elias ,  Aye, R. ,  Bertrand, S. ,  Gesharisha, J. ,  Gicheru, N. ,  Jores, Joerg ,  Liljander, Anne M. ,  Muriuki, C. ,  Naessens, Jan ,  Nene, Vishvanath ,  Njoroge, T. ,  Nyongesa, S. ,  Pelle, Roger ,  Ssajjakambwe, P. ,  Saya, R. ,  Schieck, Elise G. ,  Steinaa, Lucilla ,  Svitek, Nicholas ,  Wasilwa, J. ,  [ILRI vaccine biosciences—Planting the orchard: (ILRI’s Vaccine Platform‐ILVAC)] ,  ILRI vaccine biosciences—Planting the orchard: (ILRI’s Vaccine Platform‐ILVAC)
Poster 2013-05-15

Autor: Svitek, Nicholas Hansen, A.M. Steinaa, Lucilla Saya, R. Awino, A. Nielsen, Morten Buus, Soren Nene, Vishvanath
Enlace original: https://cgspace.cgiar.org/handle/10568/29088

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Svitek, Nicholas ,  Hansen, A.M. ,  Steinaa, Lucilla ,  Saya, R. ,  Awino, A. ,  Nielsen, Morten ,  Buus, Soren ,  Nene, Vishvanath ,  [Immunoinformatics and MHC-Tetramers, revolutionary technologies for vaccine development] ,  Immunoinformatics and MHC-Tetramers, revolutionary technologies for vaccine development
Presentation 2013

Autor: Svitek, Nicholas Steinaa, Lucilla Saya, R. Awino, Elias Nielsen, Morten Buus, Soren Nene, Vishvanath
Enlace original: https://cgspace.cgiar.org/handle/10568/79118

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Svitek, Nicholas ,  Steinaa, Lucilla ,  Saya, R. ,  Awino, Elias ,  Nielsen, Morten ,  Buus, Soren ,  Nene, Vishvanath ,  [The quest for the needle (antigen) in the haystack (pathogen): Immunoinformatics to the rescue] ,  The quest for the needle (antigen) in the haystack (pathogen): Immunoinformatics to the rescue
Book Chapter 2018

Autor: Kiara, Henry K. Steinaa, Lucilla Nene, Vishvanath Svitek, Nicholas

Theileria are important hemoprotozoan parasites of domestic and wild ruminants, transmitted by ixodid ticks leading to diseases which range from mild in apparent reactions to highly fatal diseases. Bovine-infecting T. parva and T. annulata and ovine-infecting T. lestoquardi are of major global ec...

Enlace original: https://cgspace.cgiar.org/handle/10568/96895

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Kiara, Henry K. ,  Steinaa, Lucilla ,  Nene, Vishvanath ,  Svitek, Nicholas ,  [Theileria in ruminants] ,  Theileria in ruminants
Journal Article 2015-04-30

Autor: Svitek, Nicholas Nzau, Benjamin M. Steinaa, Lucilla Nene, Vishvanath

We have developed a polymerase chain reaction-sequence-specific primers-restriction fragment length polymorphism (PCR-SSP-RFLP) method to rapidly differentiate between the A18 and A18 variant (v) BoLA haplotypes and between A14 and A15/A15v BoLA haplotypes in Holstein/Friesian cattle. We used pub...

Enlace original: https://cgspace.cgiar.org/handle/10568/66014

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Svitek, Nicholas ,  Nzau, Benjamin M. ,  Steinaa, Lucilla ,  Nene, Vishvanath ,  [A method to discriminate between closely related bovine major histocompatibility complex class I alleles by combining established PCR-SSP assays with RFLPs] ,  A method to discriminate between closely related bovine major histocompatibility complex class I alleles by combining established PCR-SSP assays with RFLPs

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