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Journal Article 2018-01-17

Autor: Steinaa, Lucilla Svitek, Nicholas Awino, Elias Saya, Rosemary Toye, Philip G.

Objectives: The objective of this study was to assess whether cytotoxic T cells (CTL) generated by the live vaccine, known as “ITM Muguga cocktail”, which is used for the cattle disease East Cost fever (ECF) in Sub-Saharan Africa, showed a broad reactivity against many different strains of the ca...

Enlace original: https://cgspace.cgiar.org/handle/10568/92437

Investigación en Agricultura
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Steinaa, Lucilla ,  Svitek, Nicholas ,  Awino, Elias ,  Saya, Rosemary ,  Toye, Philip G. ,  [Cytotoxic T lymphocytes from cattle sharing the same MHC class I haplotype and immunized with live Theileria parva sporozoites differ in antigenic specificity] ,  Cytotoxic T lymphocytes from cattle sharing the same MHC class I haplotype and immunized with live Theileria parva sporozoites differ in antigenic specificity
Journal Article 2016-06-15

Autor: Nene, Vishvanath Kiara, Henry K. Lacasta, Anna Pelle, Roger Svitek, Nicholas Steinaa, Lucilla

Tremendous progress has been made over the last ten years on East Coast fever (ECF) research. Publication of a reference genome sequence of Theileria parva, the causative agent of ECF, has led to a more thorough characterization of the genotypic and antigenic diversity of the pathogen. It also fa...

Enlace original: https://cgspace.cgiar.org/handle/10568/72680

Investigación en Agricultura
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Nene, Vishvanath ,  Kiara, Henry K. ,  Lacasta, Anna ,  Pelle, Roger ,  Svitek, Nicholas ,  Steinaa, Lucilla ,  [The biology of Theileria parva and control of East Coast fever—Current status and future trends] ,  The biology of Theileria parva and control of East Coast fever—Current status and future trends
Journal Article 2015-09-15

Autor: Svitek, Nicholas Awino, Elias Nene, Vishvanath Steinaa, Lucilla

We have recently shown that the BoLA-A18 variant haplotype (BoLA-6*01302) is more prevalent than the BoLA-A18 haplotype (BoLA-6*01301) in a sample of Holstein/Friesian cattle in Kenya. These MHC class I allelic variants differ by a single amino acid polymorphism (Glu97 to Leu97) in the peptide-bi...

Enlace original: https://cgspace.cgiar.org/handle/10568/67244

Investigación en Agricultura
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Svitek, Nicholas ,  Awino, Elias ,  Nene, Vishvanath ,  Steinaa, Lucilla ,  [BoLA-6*01301 and BoLA-6*01302, two allelic variants of the A18 haplotype, present the same epitope from the Tp1 antigen of Theileria parva] ,  BoLA-6*01301 and BoLA-6*01302, two allelic variants of the A18 haplotype, present the same epitope from the Tp1 antigen of Theileria parva
Journal Article 2015-04-30

Autor: Svitek, Nicholas Nzau, Benjamin M. Steinaa, Lucilla Nene, Vishvanath

We have developed a polymerase chain reaction-sequence-specific primers-restriction fragment length polymorphism (PCR-SSP-RFLP) method to rapidly differentiate between the A18 and A18 variant (v) BoLA haplotypes and between A14 and A15/A15v BoLA haplotypes in Holstein/Friesian cattle. We used pub...

Enlace original: https://cgspace.cgiar.org/handle/10568/66014

Investigación en Agricultura
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Svitek, Nicholas ,  Nzau, Benjamin M. ,  Steinaa, Lucilla ,  Nene, Vishvanath ,  [A method to discriminate between closely related bovine major histocompatibility complex class I alleles by combining established PCR-SSP assays with RFLPs] ,  A method to discriminate between closely related bovine major histocompatibility complex class I alleles by combining established PCR-SSP assays with RFLPs
Journal Article 2019-04-01

Autor: Nyagwange, James Awino, Elias Tijhaar, Edwin Svitek, Nicholas Pelle, Roger Nene, Vishvanath
Enlace original: https://cgspace.cgiar.org/handle/10568/99526

Investigación en Agricultura
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Nyagwange, James ,  Awino, Elias ,  Tijhaar, Edwin ,  Svitek, Nicholas ,  Pelle, Roger ,  Nene, Vishvanath ,  [Leveraging the Medicines for Malaria Venture malaria and pathogen boxes to discover chemical inhibitors of East Coast fever] ,  Leveraging the Medicines for Malaria Venture malaria and pathogen boxes to discover chemical inhibitors of East Coast fever

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