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Derda, R.Gitaka, J.Klapperich, C.M.Mace, C.R.Kumar, A.A.Lieberman, M.Linnes, J.C.Jores, JoergNasimolo, J.Ndung'u, J.M.Taracha, E.A.Weaver, A.Weibel, D.B.Kariuki, T.M.Yager, P.[Enabling the development and deployment of next generation point-of-care diagnostics]Enabling the development and deployment of next generation point-of-care diagnostics

Transcriptome analysis can provide useful data for refining genome sequence annotation. Application of massively parallel signature sequencing (MPSS) revealed reproducible transcription, in multiple MPSS cycles, from 73% of computationally predicted genes in the Theileria parva schizont lifecycle...


Shah, TushaarVilliers, Etienne P. deNene, VishvanathHass, B.Taracha, E.A.Gardner, J.M.Sansom, C.Pelle, RogerBishop, Richard P.[Using the transcriptome to annotate the genome revisited: application of massively parallel signature sequencing (MPSS)]Using the transcriptome to annotate the genome revisited: application of massively parallel signature sequencing (MPSS)

Vaccines based on recombinant Bm86 gut antigen from Boophilus microplus are a useful component of integrated control strategies against B. microplus infestations of cattle. The capacity of such vaccines to control heterologous infestations by two African tick species was investigated. The mean we...


Odongo, D.Kamau, L.Skilton, Robert A.Mwaura, S.Nitsch, C.Musoke, A.J.Taracha, E.A.Daubenberger, C.A.Bishop, Richard P.[Vaccination of cattle with TickGARD induces cross-reactive antibodies binding to conserved linear peptides of Bm86 homologues in Boophilus decoloratus]Vaccination of cattle with TickGARD induces cross-reactive antibodies binding to conserved linear peptides of Bm86 homologues in Boophilus decoloratus

A lambda gtll cDNA library was constructed using mRNA isolated from Theileria parva-infected bovine lymphocytes. Sequencing of random clones of this library resulted in the identification of a cDNA encoding bovine interleukin-16 (IL-16). The cDNA has an open reading frame of 1134 bp, and a 3? unt...


Mertens, B.Bishop, Richard P.Taracha, E.A.Morzaria, S.P.Nene, VishvanathSavadye, D.[Cloning, sequence and mRNA expression of bovine interleukin-16]Cloning, sequence and mRNA expression of bovine interleukin-16

Complete sequencing of p54-gene from 67 European, American, and West and East African Swine Fever virus (ASFV) isolates revealed that West African and European ASFV isolates classified within the predominant Genotype I according to partial sequencing of p72 were discriminated into four major sub-...


Gallardo, C.Mwaengo, D.M.Macharia, J.M.Arias, MarisaTaracha, E.A.Soler Garzón, AlvaroOkoth, S.Martin, E.Kasiti, J.Bishop, Richard P.[Enhanced discrimination of African swine fever virus isolates through nucleotide sequencing of the p54, p72, and pB602L (CVR) genes]Enhanced discrimination of African swine fever virus isolates through nucleotide sequencing of the p54, p72, and pB602L (CVR) genes

Conventional disciplinary research approach is losing momentum in the face of dynamic health challenges of the 21st century. There is a need for a new, suitable approach, to tackle these emerging and re-emerging human and animal diseases through integrating livestock and human health research in ...


Tibbo, MarkosSchelling, E.Grace, DeliaBishop, Richard P.Taracha, E.A.Kemp, Stephen J.Ameni, G.Dawo, F.Randolph, Thomas F.[Cross-disciplinary and participatory livestock and human health research for successful control of zoonoses in the developing world]Cross-disciplinary and participatory livestock and human health research for successful control of zoonoses in the developing world

Species: RuminantsTheileria parva is an intracellular protozoal parasite which causes East Coast Fever (ECF), a major constraint to cattle production in eastern and southern Africa. Characteristics of the protective CD8+ T-cell response against T. parva suggest it is focused on a limited number o...


Connelley, T.MacHugh, Niall D.Graham, S.Taracha, E.A.Burrells, A.Ngugi, D.Morrison, W. Ivan[The bovine CD8+ T-cell response to Theileria parva displays epitope immunodominance and oligoclonality]The bovine CD8+ T-cell response to Theileria parva displays epitope immunodominance and oligoclonality
Morzaria, S.P.Irvin, A.D.Taracha, E.A.Spooner, P.R.Voigt, W.P.Fujinaga, T.Katende, J.M.[Immunization against East Coast fever. The use of selected stocks of Theileria parva for immunization of cattle exposed to field challenge]Immunization against East Coast fever. The use of selected stocks of Theileria parva for immunization of cattle exposed to field challenge
Nene, VishvanathBishop, Richard P.Quackenbush, J.Pertea, M.Salzberg, S.L.Taracha, E.A.Morzaria, S.P.Fraser, C.M.Gardner, M.[Genomics of Theileria parva]Genomics of Theileria parva

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