Theileria parva is an intracellular sporozoan parasite that infects and transforms bovine lymphocytes, causing a severe lymphoproliferative disease known as East Coast fever in eastern, central and southern Africa. In this article, Declan McKeever and colleagues summarize the current understandin...
McKeever, Declan J.
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Taracha, E.L.N.
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Morrison, W. Ivan
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Musoke, A.J.
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Morzaria, S.P.
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[Protective immune mechanisms against Theileria parva: Evolution of vaccine development strategies]
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Protective immune mechanisms against Theileria parva: Evolution of vaccine development strategies
Studies of the immune responses of cattle to Theileria parva have provided evidence that immunity to the parasite can operate at two levels, namely the sporozoite and the schizont-infected lymphoblast. Antibodies that neutralize the infectivity of sporozoites have been detected in the serum of hy...
Morrison, W. Ivan
,
Taracha, E.L.N.
,
McKeever, Declan J.
,
[Theileriosis: Progress towards vaccine development through understanding immune responses to the parasite]
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Theileriosis: Progress towards vaccine development through understanding immune responses to the parasite
Contagious bovine pleuropneumonia (CBPP) is one of the most important transboundary animal diseases in Africa. In recent years, CBPP has been found in countries like Botswana from where it was previously eradicated (Amanfu et al., 1998). There is growing evidence to indicate that the incidence of...