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Goddeeris, B.M.Morrison, W. IvanTaracha, E.L.N.McKeever, Declan J.[East Coast Fever (Theileria parva). Cell-mediated immunity and protection]East Coast Fever (Theileria parva). Cell-mediated immunity and protection

There is strong evidence that class I MHC-restricted parasite-specific CD8+ CTL protect cattle against the protozoan parasite Theileria parva. As part of an effort to develop a subunit vaccine for the induction of these responses, we have investigated the factors involved in the generation of T. ...


Taracha, E.L.N.Awino, EliasMcKeever, Declan J.[Distinct CD4 + T cell helper requirements in Theileria parva-immune and -naive bovine CTL precursors]Distinct CD4 + T cell helper requirements in Theileria parva-immune and -naive bovine CTL precursors
Howard, C.J.Sopp, P.Parsons, K.R.McKeever, Declan J.Taracha, E.L.N.Jones, B.V.MacHugh, Niall D.Morrison, W. Ivan[Distinction of naive and memory BoCD4 lymphocytes in calves with a monoclonal antibody, CC76, to a restricted determinant of the bovine leukocyte-common antigen, CD45]Distinction of naive and memory BoCD4 lymphocytes in calves with a monoclonal antibody, CC76, to a restricted determinant of the bovine leukocyte-common antigen, CD45

The importance of T-cell-mediate immune responses in the control of intracellular protozoan parasites is now well established 1-3. The killing of parasitized cells by T cells and cytokine-mediated effects on growth and viability of the intracellular parasites have both been implicated as effector...


Morrison, W. IvanTaracha, E.L.N.McKeever, Declan J.[Contribution of T-cell responses to immunity and pathogenesis in infection with Theileria parva]Contribution of T-cell responses to immunity and pathogenesis in infection with Theileria parva
Mwangi, D.M.Graham, S.P.Pelle, RogerHonda, Y.Tonukari, N.J.Yamage, I.M.Glew, E.J.Villiers, Etienne P. deShah, TushaarBishop, Richard P.Abuya, E.Awino, EliasGachanja, J.Luyai, A.E.Mbwika, F.Muthiani, A.M.Ndegwa, D.M.Njahira, Moses N.Nyanjui, J.K.Onono, F.O.Osaso, J.Saya, R.M.Wildmann, C.Fraser, C.M.Maudlin, I.Gardner, M.J.Morzaria, S.P.Loosmore, S.Gilbert, S.C.Audonnet, J.C.Bruggen, P. van derNene, VishvanathTaracha, E.L.N.[Exploiting host immunity and parasite genomics to develop a robust sub-unit vaccine against East Coast fever in cattle - Where are we?]Exploiting host immunity and parasite genomics to develop a robust sub-unit vaccine against East Coast fever in cattle - Where are we?

Contagious bovine pleuropneumonia (CBPP) is one of the most important transboundary animal diseases in Africa. In recent years, CBPP has been found in countries like Botswana from where it was previously eradicated (Amanfu et al., 1998). There is growing evidence to indicate that the incidence of...


Mbithi, F.Wesonga, H.O.Thiaucourt, FrancoisTaracha, E.L.N.[Immune responses in cattle vaccinated against contagious bovine pleuropneumonia: preliminary results]Immune responses in cattle vaccinated against contagious bovine pleuropneumonia: preliminary results
McKeever, Declan J.Taracha, E.L.N.Innes, E.L.MacHugh, Niall D.Awino, EliasGoddeeris, B.M.Morrison, W. Ivan[Adoptive transfer of immunity to Theileria parva in the CD8+ fraction of responding effluent lymph]Adoptive transfer of immunity to Theileria parva in the CD8+ fraction of responding effluent lymph

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