Contagious bovine pleuropneumonia (CBPP) is a lung disease caused by the bacterial pathogen Mycoplasma mycoides ssp. mycoides small colony type (MmmSC). It has been spreading due to a number of factors including poor vaccine efficacy and poor sensitivity of current diagnostic tests. The purpose o...
Jores, Joerg
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Nkando, I.
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Sterner-Kock, Anja
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Haider, W.
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Poole, Elizabeth J.
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Unger, H.
,
Muriuki, C.
,
Wesonga, H.O.
,
Taracha, E.L.N.
,
[Assessment of in vitro interferon-gamma responses from peripheral blood mononuclear cells of cattle infected with Mycoplasma mycoides ssp. mycoides small colony type]
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Assessment of in vitro interferon-gamma responses from peripheral blood mononuclear cells of cattle infected with Mycoplasma mycoides ssp. mycoides small colony type
Immunity against the bovine protozoan parasite Theileria parva has previously been shown to be mediated through lysis of parasite-infected cells by MHC class I restricted CD8+ cytotoxic T lymphocytes. It is hypothesized that identification of CTL target schizont antigens will aid the development ...
Graham, S.P.
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Honda, Y.
,
Pelle, Roger
,
Mwangi, D.M.
,
Glew, E.J.
,
Villiers, Etienne P. de
,
Shah, Tushaar
,
Bishop, Richard P.
,
Bruggen, P. van der
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Nene, Vishvanath
,
Taracha, E.L.N.
,
[A novel strategy for the identification of antigens that are recognised by bovine MHC class I restricted cytotoxic T cells in a protozoan infection using reverse vaccinology]
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A novel strategy for the identification of antigens that are recognised by bovine MHC class I restricted cytotoxic T cells in a protozoan infection using reverse vaccinology
Flow cytometry, enzyme-linked immunospot (ELISpot) and cellular cytotoxicity assays are powerful tools for studying the cellular immune response towards intracellular pathogens and vaccines in livestock species. Lymphocytes from immunized animals can be purified using Ficoll-Paque density gradien...
Svitek, Nicholas
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Taracha, E.L.N.
,
Saya, R.
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Awino, Elias
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Nene, Vishvanath
,
Steinaa, Lucilla
,
[Analysis of the cellular immune responses to vaccines]
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Analysis of the cellular immune responses to vaccines
Taracha, E.L.N.
,
Irvin, A.D.
,
Morzaria, S.P.
,
Moloo, S.K.
,
Katende, J.M.
,
Kiarie, J.N.
,
[Effect of chronic trypanosomiasis on immunization against East Coast fever]
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Effect of chronic trypanosomiasis on immunization against East Coast fever
We evaluated sexual recombination in the apicomplexan parasite Theileria parva using genome-wide marker analysis of haploid sporozoite populations obtained from infected Rhipicephalus appendiculatus ticks. Analysis of 231 parasite clones derived by in vitro infection of bovine lymphocytes reveale...
Katzer, F.
,
Ngugi, D.
,
Oura, C.
,
Bishop, Richard P.
,
Taracha, E.L.N.
,
Walker, A.R.
,
McKeever, Declan J.
,
[Extensive genotypic diversity in a recombining population of the apicomplexan parasite Theileria parva]
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Extensive genotypic diversity in a recombining population of the apicomplexan parasite Theileria parva
Howard, C.J.
,
Sopp, P.
,
Parsons, K.R.
,
McKeever, Declan J.
,
Taracha, E.L.N.
,
Jones, B.V.
,
MacHugh, Niall D.
,
Morrison, W. Ivan
,
[Distinction of naive and memory BoCD4 lymphocytes in calves with a monoclonal antibody, CC76, to a restricted determinant of the bovine leukocyte-common antigen, CD45]
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Distinction of naive and memory BoCD4 lymphocytes in calves with a monoclonal antibody, CC76, to a restricted determinant of the bovine leukocyte-common antigen, CD45
Morzaria, S.P.
,
Irvin, A.D.
,
Voigt, W.P.
,
Taracha, E.L.N.
,
[Effect of timing and intensity of challenge following immunization against East Coast fever]
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Effect of timing and intensity of challenge following immunization against East Coast fever
Taracha, E.L.N.
,
Irvin, A.D.
,
Morzaria, S.P.
,
Moloo, S.K.
,
Katende, J.M.
,
Kiarie, J.N.
,
[Immunization against East Coast Fever. Effect of chronic trypanosomiais on the Development of immunity]
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Immunization against East Coast Fever. Effect of chronic trypanosomiais on the Development of immunity