African trypansosomes are tsetse-transmitted parasites of chief importance in causing disease in livestock in regions of sub-Saharan Africa. Previous studies have demonstrated that certain breeds of cattle are relatively resistant to infection with trypanosomes, and others are more susceptible. B...
Haas, K.M.
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Taylor, K.A.
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MacHugh, Niall D.
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Kreeger, J.M.
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Estes, D.M.
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[Enhancing effects of anti-CD40 treatment on the immune response of SCID-bovine mice to Trypanosoma congolense infection]
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Enhancing effects of anti-CD40 treatment on the immune response of SCID-bovine mice to Trypanosoma congolense infection
Memory T- and B-cell responses to trypanosome antigens were measured in peripheral blood mononuclear cells, spleen and lymph node cells obtained from 4 trypanotolerant N'Dama cattle which had been exposed to 6 experimental infections with Trypanosoma congolense. These cattle were treated with try...
Lutje, V.
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Taylor, K.A.
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Boulange, A.F.
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Authié, E.
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[Trypanosoma congolense: Tissue distribution of long-term T- and B-cell responses in cattle]
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Trypanosoma congolense: Tissue distribution of long-term T- and B-cell responses in cattle
Trypanosomosis in domestic livestock negatively impacts food production and economic growth in many parts of the world, particularly in sub-Saharan Africa. Current methods of control are inadequate to prevent the enormous annual socio-economic losses resulting from this disease. Hope for a vaccin...
Taylor, K.A.
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[Immune responses of cattle to African trypanosomes: Protective or pathogenic?]
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Immune responses of cattle to African trypanosomes: Protective or pathogenic?