Quantitative trait loci (QTL) associated with resistance to an intestinal worm in a well-defined murine model are described. These have been identified in an F(2) population derived from resistant (SWR) and susceptible (CBA) parental mouse strains infected with the gastro-intestinal nematode par...
Kitani, H.
,
Naessens, Jan
,
Momotani, E.
,
Yagi, Y.
,
Sekikawa, K.
,
Teale, A.J.
,
Iraqi, F.A.
,
[The roles of TNF-alpha in genetic resistance of mice to Trypanosoma congolense infection]
,
The roles of TNF-alpha in genetic resistance of mice to Trypanosoma congolense infection
The cartography in the high resolution of quantitative locus of character (QTL) is an important step towards the positional cloning or the positional identification of candidate genes. Recently, the use of descendants at the advanced inter-junction has been described for the dissection and the pr...
Iraqi, F.A.
,
Kemp, Stephen J.
,
Teale, A.J.
,
[Towards identification and cloning of the trypanotolerance genes in mouse]
,
Towards identification and cloning of the trypanotolerance genes in mouse
In previous studies, the resistance to infection by Trypanosoma congolense has been localized in a region of chromosome 17 consisting the gene of TNF alpha. On the other hand, it has been Reported that the TNF alpha has a trypanolitic activity. So, we have started to study the expression of TN al...
Iraqi, F.A.
,
Sileghem, M.R.
,
Teale, A.J.
,
[TNF-alpha expression in trypanosomiasis resistant and susceptible mouse strains during infection with Trypanosoma congolense]
,
TNF-alpha expression in trypanosomiasis resistant and susceptible mouse strains during infection with Trypanosoma congolense