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Inbred strains of laboratory mice exhibit marked differences in survival time following infection with Trypanosoma congolense, the principal cause of trypanosomiasis in African livestock.The difference in survival time between the relatively resistant C57BL/6 J and more susceptible BALB/c inbred ...


Clapcott, S.J.Teale, A.J.Kemp, Stephen J.[Evidence for genomic imprinting of the major QTL controlling susceptibility to trypanosomiasis in mice]Evidence for genomic imprinting of the major QTL controlling susceptibility to trypanosomiasis in mice

We have previously reported the results of genome-wide searches in two murine F2 populations for QTLs that influence survival following Trypanosoma congolense infection. Three loci, Tir1, Tir2, and Tir3, were identified and mapped to mouse Chromosomes (Chrs) 17, 5, and 1 respectively, with confid...


Iraqi, F.A.Clapcott, S.J.Kumari, P.Haley, C.S.Kemp, Stephen J.Teale, A.J.[Fine mapping of trypanosomiasis resistance loci in murine advanced intercross lines]Fine mapping of trypanosomiasis resistance loci in murine advanced intercross lines

Natural resistance to African trypanosomiasis in certain Bos taurus cattle in West Africa, called trypanotolerance, may hold solutions for control of this economically crippling disease. Comparison of immune responses between trypanotolerant and trypanosusceptible cattle have shown some differenc...


Naessens, JanTeale, A.J.Sileghem, M.R.[Identification of mechanisms of natural resistance to African trypanosomiasis in cattle]Identification of mechanisms of natural resistance to African trypanosomiasis in cattle

Trypanosomosis, or sleeping sickness, is a major disease constraint on livestock productivity in sub-Saharan Africa. To identify quantitative trait loci (QTL) controlling resistance to trypanosomosis in cattle, an experimental cross was made between trypanotolerant African N'Dama (Bos taurus) and...


Hanotte, Olivier H.Ronin, Y.Agaba, MorrisNilsson, P.Gelhaus, A.Horstmann, R.Sugimoto, Y.Kemp, Stephen J.Gibson, John P.Korol, A.Soller, M.Teale, A.J.[Mapping of quantitative trait loci controlling trypanotolerance in a cross of tolerant West African N'Dama and susceptible East African Boran cattle]Mapping of quantitative trait loci controlling trypanotolerance in a cross of tolerant West African N'Dama and susceptible East African Boran cattle
Kemp, Stephen J.Spooner, R.L.Teale, A.J.[A comparative study of major histocompatibility complex antigens in East African and European cattle breeds]A comparative study of major histocompatibility complex antigens in East African and European cattle breeds

A panel of 81 new polymorphic bovine microsatellite markers is described, together with further information on a previously reported group of 16 markers. The mean polymorphism information content of the 97 markers determined in 20 cattle was 0.66. Seventy-three of these markers have been assigned...


Kemp, Stephen J.Hishida, OWambugu, J.Rink, A.Longeri, M.L.Ma, R.Z.Da, Y.Lewin, H.A.Barendse, W.Teale, A.J.[A panel of polymorphic bovine, ovine and caprine microsatellite markers]A panel of polymorphic bovine, ovine and caprine microsatellite markers

A small number of west African Bos taurus cattle breeds, including the N'Dama, constitute a valuable genetic resource by virtue of their ability to remain productive under trypanosomiasis challenge. However, introgression of Bos indicus genes into the trypanotolerant breeds, particularly by intro...


Teale, A.J.Wambugu, J.Gwakisa, P.S.Stranzinger, G.Bradley, D.Kemp, Stephen J.[A polymorphism in randomly amplified DNA which differentiates the Y chromosomes of Bos indicus and Bos taurus]A polymorphism in randomly amplified DNA which differentiates the Y chromosomes of Bos indicus and Bos taurus

To optimize designs to implement marker-assisted introgression programs aiming to introgress three unlinked quantitative trait loci (QTL), the present paper studies different alternatives versus a traditional backcross or intercross phase. Four alternative backcross strategies appear to be more a...


Koudande, O.D.Iraqi, F.A.Thomson, P.C.Teale, A.J.Arendonk, Johan A.M. van[Strategies to optimize marker-assisted introgression of multiple unlinked QTL]Strategies to optimize marker-assisted introgression of multiple unlinked QTL
Iraqi, F.A.Kemp, Stephen J.Teale, A.J.[Fine mapping of trypanosomiasis resistance QTLs in mice using advanced intercross lines]Fine mapping of trypanosomiasis resistance QTLs in mice using advanced intercross lines
Autor: Teale, A.J.

This paper reviews papers that deals with bovine lymphocyte antigen (BoLA) system. It discusses when characterization of the bovine MHC began, workshops conducted and their concerns which included serological characterization of the products of the MHC, the bovine lymphocyte antigen (BoLA) system...


Teale, A.J.[Introduction to the BoLA system]Introduction to the BoLA system

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