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Autor: Teale, A.J.

Presents reports of the gene mapping laboratories and of those laboratories and groups concerned directly with trypanotolerance research and summarises the final round table discussion, and the workshop's recommendations concerning genome mapping development and the production and use of trypanot...


Teale, A.J.[Bovine genome. Mapping and trypanotolerance. Proceedings of a workshop]Bovine genome. Mapping and trypanotolerance. Proceedings of a workshop
Kemp, Stephen J.Maillard, J.C.Teale, A.J.[A polymorphism in the bovine gamma-S-crystallin gene revealed by allele-specific amplification]A polymorphism in the bovine gamma-S-crystallin gene revealed by allele-specific amplification

Two bovine bacterial artificial chromosome clones were screened by PCR to amplify the tumour necrosis factor alpha (TNFA) gene. DNA extraction and Southern blotting and probing with a (GT)10 oligonucleotide were performed, followed by cloning into the pUC19 vector. A 0.9 kb fragment containing se...


Wambugu, J.Kanguha, E.Hanotte, Olivier H.Davis, S.Taylor, J.Skow, L.Brunner, R.Schwerin, M.Teale, A.J.Iraqi, F.A.[Identification of two polymorphic microsatellite repeats on a bovine TNFA-containing BAC clone]Identification of two polymorphic microsatellite repeats on a bovine TNFA-containing BAC clone
Toye, Philip G.Teale, A.J.[Gene transfection in mammalian cells and its application in studies of immunity to East Coast fever]Gene transfection in mammalian cells and its application in studies of immunity to East Coast fever

The C57BL/6 BALB/c and A/J inbred laboratory mouse strains often express different response phenotypes when challenged with a variety of infectious agents (Morrison et al. 1978; Bradley 1977; Hormmaeche et al. 1985). In view of the pivotal role of tumor necrosis factor Tnfa in innate immunity, we...


Iraqi, F.A.Teale, A.J.[Cloning and sequencing of the Tnfa genes of three inbred mouse strains]Cloning and sequencing of the Tnfa genes of three inbred mouse strains

The tumor necrosis factor (TNF) locus comprises the tandemly arranged genes coding for Tnfa (cachectin) and Tnfb (lymphotoxin-alpha) (Semon et al 1987). In mice, the TNF locus is located on chromosome 17 (MMU17) in the major histocompatibility complex (MHC) region. Tnfa and soluble lymphotoxin al...


Iraqi, F.A.Teale, A.J.[Polymorphism in the microsatellite located in the promoters of the Tnfa and Tnfb genes of different mouse strains]Polymorphism in the microsatellite located in the promoters of the Tnfa and Tnfb genes of different mouse strains

In view of the Tnfa gene location within the major histocompatibility (MHC) region and reports of its importance in disease protection activity, this paper examines the TNF a genes of a number of different mouse strains which were known to be of different disease response phenotypes. Twelve inbre...


Iraqi, F.A.Teale, A.J.[Polymorphisms, in the Tnfa gene of different inbred mouse strains]Polymorphisms, in the Tnfa gene of different inbred mouse strains
Autor: Teale, A.J.

The unique potential of biotechnology to provide new solutions to old problems constraining the contribution of livestock to farming systems in the developing world is emphasized in this paper. An overview of biotechnological aspects of livestock research within the CGIAR, including a description...


Teale, A.J.[Biotechnology: A key element in the CGIAR's livestock research programme]Biotechnology: A key element in the CGIAR's livestock research programme
Joosten, I.Teale, A.J.Poel, A. van derHensen, E.J.[Biochemical evidence of the expression of two major histocompatibility complex class I genes on bovine peripheral blood mononuclear cells]Biochemical evidence of the expression of two major histocompatibility complex class I genes on bovine peripheral blood mononuclear cells

Under most circumstances, certain breeds of domestic ruminants show a remarkable resistance to the effects of African trypanosomiasis: they can tolerate the presence of parasites while apparently controlling levels of parasitaemia and, crucially, not showing the the severe anaemia and production ...


Kemp, Stephen J.Teale, A.J.[Genetic basis of trypanotolerance in cattle and mice]Genetic basis of trypanotolerance in cattle and mice

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