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Four single-strand conformation variants of the bovine tumor necrosis factor alpha gene by analysis of PCR-amplified fragments were identified. The variants are inherited in Mendelian fashion and are informative for linkage mapping. We have mapped the bovine gene to Chromosome (Chr) 23 in a panel...


Agaba, MorrisKemp, Stephen J.Barendse, W.Teale, A.J.[Polymorphism at the bovine tumor necrosis factor alpha locus and assignment to BTA 23]Polymorphism at the bovine tumor necrosis factor alpha locus and assignment to BTA 23

The tumor necrosis factor (TNF) locus comprises the tandemly arranged genes coding for Tnfa (cachectin) and Tnfb (lymphotoxin-alpha) (Semon et al 1987). In mice, the TNF locus is located on chromosome 17 (MMU17) in the major histocompatibility complex (MHC) region. Tnfa and soluble lymphotoxin al...


Iraqi, F.A.Teale, A.J.[Polymorphism in the microsatellite located in the promoters of the Tnfa and Tnfb genes of different mouse strains]Polymorphism in the microsatellite located in the promoters of the Tnfa and Tnfb genes of different mouse strains

In view of the Tnfa gene location within the major histocompatibility (MHC) region and reports of its importance in disease protection activity, this paper examines the TNF a genes of a number of different mouse strains which were known to be of different disease response phenotypes. Twelve inbre...


Iraqi, F.A.Teale, A.J.[Polymorphisms, in the Tnfa gene of different inbred mouse strains]Polymorphisms, in the Tnfa gene of different inbred mouse strains

A panel of 81 new polymorphic bovine microsatellite markers is described, together with further information on a previously reported group of 16 markers. The mean polymorphism information content of the 97 markers determined in 20 cattle was 0.66. Seventy-three of these markers have been assigned...


Kemp, Stephen J.Hishida, OWambugu, J.Rink, A.Longeri, M.L.Ma, R.Z.Da, Y.Lewin, H.A.Barendse, W.Teale, A.J.[A panel of polymorphic bovine, ovine and caprine microsatellite markers]A panel of polymorphic bovine, ovine and caprine microsatellite markers

A small number of west African Bos taurus cattle breeds, including the N'Dama, constitute a valuable genetic resource by virtue of their ability to remain productive under trypanosomiasis challenge. However, introgression of Bos indicus genes into the trypanotolerant breeds, particularly by intro...


Teale, A.J.Wambugu, J.Gwakisa, P.S.Stranzinger, G.Bradley, D.Kemp, Stephen J.[A polymorphism in randomly amplified DNA which differentiates the Y chromosomes of Bos indicus and Bos taurus]A polymorphism in randomly amplified DNA which differentiates the Y chromosomes of Bos indicus and Bos taurus

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