The drivers of vaccine development are many and varied. They include, for example, recognition of the burden of a vaccine-targeted disease, prioritisation of the multiple problems associated with a disease, consideration of the differing socio-economic situations under which vaccines are used, th...
Thomas, L.F.
,
Bellet, C.
,
Rushton, Jonathan
,
[Using economic and social data to improve veterinary vaccine development: Learning lessons from human vaccinology]
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Using economic and social data to improve veterinary vaccine development: Learning lessons from human vaccinology
Background
The neglected zoonotic diseases (NZD) are an understudied group that are a major cause of illness throughout the developing world. In general, little is known about the prevalence and burden of NZDs in affected communities, particularly in relation to other infectious diseases with whi...
Fèvre, Eric M.
,
Glanville, William A. de
,
Thomas, L.F.
,
Cook, Elizabeth A.J.
,
Kariuki, S.
,
Wamae, C.N.
,
[An integrated study of human and animal infectious disease in the Lake Victoria crescent small-holder crop-livestock production system, Kenya]
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An integrated study of human and animal infectious disease in the Lake Victoria crescent small-holder crop-livestock production system, Kenya
Eimeriosis is caused by a protozoan infection affecting most domestic animal species. Outbreaks in cattle are associated with various environmental factors in temperate climates but limited work has been done in tropical settings. The objective of this work was to determine the prevalence and env...
Makau, D.N.
,
Gitau, G.K.
,
Muchemi, G.K.
,
Thomas, L.F.
,
Cook, Elizabeth A.J.
,
Wardrop, N.A.
,
Fèvre, Eric M.
,
Glanville, William A. de
,
[Environmental predictors of bovine Eimeria infection in western Kenya]
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Environmental predictors of bovine Eimeria infection in western Kenya
Objectives Leptospirosis has been documented in slaughterhouse workers around the world. Risk factors include smoking and drinking at work, and performing tasks such as cleaning offal. This paper examined risk factors for leptospirosis seropositivity in slaughterhouse workers in western Kenya.
M...
Cook, Elizabeth A.J.
,
Glanville, William A. de
,
Thomas, L.F.
,
Kariuki, S.
,
Bronsvoort, B.M. de C.
,
Fèvre, Eric M.
,
[Risk factors for leptospirosis seropositivity in slaughterhouse workers in western Kenya]
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Risk factors for leptospirosis seropositivity in slaughterhouse workers in western Kenya
Rift Valley fever virus (RVFV) is a zoonotic arbovirus affecting livestock and people. This study was conducted in western Kenya where RVFV outbreaks have not previously been reported. The aims were to document the seroprevalence and risk factors for RVFV antibodies in a community-based sample fr...
Cook, Elizabeth A.J.
,
Grossi-Soyster, E.N.
,
Glanville, William A. de
,
Thomas, L.F.
,
Kariuki, S.
,
Bronsvoort, B.M. de C.
,
Wamae, C.N.
,
LaBeaud, A.D.
,
Fèvre, Eric M.
,
[The sero-epidemiology of Rift Valley fever in people in the Lake Victoria Basin of western Kenya]
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The sero-epidemiology of Rift Valley fever in people in the Lake Victoria Basin of western Kenya
Background
Inadequate facilities and hygiene at slaughterhouses can result in contamination of meat and occupational hazards to workers. The objectives of this study were to assess current conditions in slaughterhouses in western Kenya and the knowledge, and practices of the slaughterhouse worker...
Cook, Elizabeth A.J.
,
Glanville, William A. de
,
Thomas, L.F.
,
Kariuki, S.
,
Bronsvoort, B.M. de C.
,
Fèvre, Eric M.
,
[Working conditions and public health risks in slaughterhouses in western Kenya]
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Working conditions and public health risks in slaughterhouses in western Kenya
Alphaviruses, such as chikungunya virus, and flaviviruses, such as dengue virus, are (re)-emerging arboviruses that are endemic in tropical environments. In Africa, arbovirus infections are often undiagnosed and unreported, with febrile illnesses often assumed to be malaria. This cross-sectional ...
Grossi-Soyster, E.N.
,
Cook, Elizabeth A.J.
,
Glanville, William A. de
,
Thomas, L.F.
,
Krystosik, A.R.
,
Lee, J.
,
Wamae, C.N.
,
Kariuki, S.
,
Fèvre, Eric M.
,
LaBeaud, A.D.
,
[Serological and spatial analysis of alphavirus and flavivirus prevalence and risk factors in a rural community in western Kenya]
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Serological and spatial analysis of alphavirus and flavivirus prevalence and risk factors in a rural community in western Kenya
Growth performance of pigs on smallholder farms in the tropics is low. Lack of feedstuffs, seasonal feed shortages, and feeding nutritionally unbalanced diets contribute to slow growth. Low-cost balanced diets are needed to improve pig performance. In this study, we estimated the nutrient require...
Carter, Natalie A.
,
Dewey, C.E.
,
Thomas, L.F.
,
Lukuyu, Ben A.
,
Grace, Delia
,
Lange, C.F.M. de
,
[Nutrient requirements and low-cost balanced diets, based on seasonally available local feedstuffs, for local pigs on smallholder farms in western Kenya]
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Nutrient requirements and low-cost balanced diets, based on seasonally available local feedstuffs, for local pigs on smallholder farms in western Kenya
Taenia spp. infections, particularly cysticercosis, cause considerable health impacts in endemic countries. Despite previous evidence of spatial clustering in cysticercosis and the role of environmental factors (e.g. temperature and humidity) in the survival of eggs, little research has explored ...
Wardrop, N.A.
,
Thomas, L.F.
,
Atkinson, P.M.
,
Glanville, William A. de
,
Cook, Elizabeth A.J.
,
Wamae, C.N.
,
Gabriël, S.
,
Dorny, P.
,
Harrison, L.J.S.
,
Fèvre, Eric M.
,
[The influence of socio-economic, behavioural and environmental factors on Taenia spp. transmission in western Kenya: Evidence from a cross-sectional survey in humans and pigs]
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The influence of socio-economic, behavioural and environmental factors on Taenia spp. transmission in western Kenya: Evidence from a cross-sectional survey in humans and pigs
Background Taenia solium is a zoonotic helminth with the potential to cause life threatening epilepsy in people through the aberrant larval infection of the brain called Neurocysticercosis (NCC). The pig is the intermediate host for T. solium where the larval form, cysticercus cellulosae, normall...
Nsadha, Z.
,
Thomas, L.F.
,
Fèvre, Eric M.
,
Nasinyama, G.
,
Ojok, L.
,
Waiswa, C.
,
[Prevalence of porcine cysticercosis in the Lake Kyoga Basin, Uganda]
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Prevalence of porcine cysticercosis in the Lake Kyoga Basin, Uganda