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The expression and characterization of a recombinant antigen termed Ov-47 are described. Ov-47 was identified and isolated from a lambda gt-11 eDNA expression library derived from adult female Onclrucercu volvukrs mRNA using rabbit antiserum raised against the surface proteins of O. vulvulcw fema...


Ghoyomu, S.M.Souopgui, J.Pelle, RogerTitanji, V.P.K.[Expression and characterization of Ov-47, a dominant antigen of Onchocerca volvulus]Expression and characterization of Ov-47, a dominant antigen of Onchocerca volvulus

Objective: To determine the role of an immunodominant antigen OvPG-1 in human onchocerciasis. Design: Cross-sectional study of subjects living in three onchocerciasis endemic areas. Setting: Mbonge and Tubah divisions of Western Cameroon and in Esmeralda Province of Ecuador. Subjects: There were ...


Amambua, A.N.Tachu, J.B.Ghogomu, S.M.Pelle, RogerTitanji, V.P.K.[Characterisation of a heparan sulfate proteoglycan homologue OVPG-1 from Onchocerca volvulus]Characterisation of a heparan sulfate proteoglycan homologue OVPG-1 from Onchocerca volvulus
Cho-Ngwa, F.Assam-Assam, J.P.Ane-Anyangwe, I.Skilton, Robert A.Pelle, RogerKitavi, M.Nzuki, I.Nyonka, J.Tedom, J.C.Beng, V.P.Akoachere, Jane-FrancisNjie, M.Titanji, V.P.K.[Molecular and phenotypic characterisation of mycobacterium tuberculosis complex]Molecular and phenotypic characterisation of mycobacterium tuberculosis complex

The development of a sterilizing and cost-effective vaccine against malaria remains a major problem despite recent advances. In this study, it is demonstrated that two antigens of P. falciparum UB05, UB09 and their chimera UB05-09 can serve as protective immunity markers by eliciting higher T-cel...


Dinga, J.N.Njimoh, D.L.Kiawa, B.Djikeng, AppolinaireNyasa, R.B.Nkuo-Akenji, T.Pelle, RogerTitanji, V.P.K.[Differential T-cell responses to a chimeric Plasmodium falciparum antigen; UB05-09, correlates with acquired immunity to malaria]Differential T-cell responses to a chimeric Plasmodium falciparum antigen; UB05-09, correlates with acquired immunity to malaria

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