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Journal Article 1996

Recombinant bovine interferon gamma inhibits the growth of Cowdria ruminantium but fails to induce major histocompatibility complex class II following infection of endothelial cells

Autor: Totte, P. Vachiery, N. Martínez, D. Trap, I. Ballingall, K.T. MacHugh, Niall D. Bensaid, A. Werenne, J.

Recombinant bovine IFN gamma is a potent inhibitor of Cowdria ruminantium growth in vitro irrespective of the rickettsial stock, or the origin of the endothelial cells. These results suggest an important role for IFN gamma in protective immune responses against C. ruminantium infections. Here we ...

Enlace original: https://cgspace.cgiar.org/handle/10568/29855

Investigación en Agricultura

COWDRIA RUMINATUM

INFECTION

CELLS

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Totte, P. , Vachiery, N. , Martínez, D. , Trap, I. , Ballingall, K.T. , MacHugh, Niall D. , Bensaid, A. , Werenne, J. , [Recombinant bovine interferon gamma inhibits the growth of Cowdria ruminantium but fails to induce major histocompatibility complex class II following infection of endothelial cells] , Recombinant bovine interferon gamma inhibits the growth of Cowdria ruminantium but fails to induce major histocompatibility complex class II following infection of endothelial cells

Journal Article 1999

Immune responses to Cowdria ruminantium infections

Autor: Totte, P. Bensaid, A. Mahan, S.M. Martínez, D. McKeever, Declan J.

Understanding the basis of protective immunity to Cowdria ruminantium will facilitate the development of an effective subunit vaccine against heartwater in ruminants and contribute to a better definition of protective immune mechanisms to obligate intracellular pathogens in general. Until recentl...

Enlace original: https://cgspace.cgiar.org/handle/10568/33105

Investigación en Agricultura

COWDRIA RUMINANTIUM

IMMUNE RESPONSE

ANTIBODIES

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Totte, P. , Bensaid, A. , Mahan, S.M. , Martínez, D. , McKeever, Declan J. , [Immune responses to Cowdria ruminantium infections] , Immune responses to Cowdria ruminantium infections

Journal Article 2000

A highly sensitive, non-radioactive assay for T cell activation in cattle: Applications in screening for antigens recognised by CD4+ and CD8+ T cells

Autor: Ballingall, K.T. Mwangi, D.M. MacHugh, Niall D. Taracha, E.L.N. Totte, P. McKeever, Declan J.

We describe a highly sensitive, non-radioactive assay for T cell activation, based on the rapid induction of class II MHC expression by constitutively negative bovine endothelial cells, when cultured in the presence of supernatants derived from activated bovine T cells. We demonstrate the effecti...

Enlace original: https://cgspace.cgiar.org/handle/10568/33010

Investigación en Agricultura

CATTLE

ANTIGENS

BOVIDAE

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Ballingall, K.T. , Mwangi, D.M. , MacHugh, Niall D. , Taracha, E.L.N. , Totte, P. , McKeever, Declan J. , [A highly sensitive, non-radioactive assay for T cell activation in cattle: Applications in screening for antigens recognised by CD4+ and CD8+ T cells] , A highly sensitive, non-radioactive assay for T cell activation in cattle: Applications in screening for antigens recognised by CD4+ and CD8+ T cells

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Recombinant bovine interferon gamma inhibits the growth of Cowdria ruminantium but fails to induce major histocompatibility complex class II following infection of endothelial cells

Immune responses to Cowdria ruminantium infections

A highly sensitive, non-radioactive assay for T cell activation in cattle: Applications in screening for antigens recognised by CD4+ and CD8+ T cells