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Journal Article 2019-05-01

Autor: Sitta, Tatjana Henson, Sonal P. Morrison, W. Ivan Toye, Philip G.
Enlace original: https://cgspace.cgiar.org/handle/10568/101122

Investigación en Agricultura
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Sitta, Tatjana ,  Henson, Sonal P. ,  Morrison, W. Ivan ,  Toye, Philip G. ,  [Similar levels of diversity in the gene encoding the p67 sporozoite surface protein of Theileria parva are observed in blood samples from buffalo and cattle naturally infected from buffalo] ,  Similar levels of diversity in the gene encoding the p67 sporozoite surface protein of Theileria parva are observed in blood samples from buffalo and cattle naturally infected from buffalo
Journal Article 2016-07-15

Autor: Hemmink, J.D. Weir, W. MacHugh, Niall D. Graham, S.P. Patel, Ekta Paxton, E. Shiels, B. Toye, Philip G. Morrison, W. Ivan Pelle, Roger

An infection and treatment protocol is used to vaccinate cattle against Theileria parva infection. Due to incomplete cross-protection between different parasite isolates, a mixture of three isolates, termed the Muguga cocktail, is used for vaccination. While vaccination of cattle in some regions ...

Enlace original: https://cgspace.cgiar.org/handle/10568/73303

Investigación en Agricultura
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Hemmink, J.D. ,  Weir, W. ,  MacHugh, Niall D. ,  Graham, S.P. ,  Patel, Ekta ,  Paxton, E. ,  Shiels, B. ,  Toye, Philip G. ,  Morrison, W. Ivan ,  Pelle, Roger ,  [Limited genetic and antigenic diversity within parasite isolates used in a live vaccine against Theileria parva] ,  Limited genetic and antigenic diversity within parasite isolates used in a live vaccine against Theileria parva
Journal Article 2018-01-17

Autor: Steinaa, Lucilla Svitek, Nicholas Awino, Elias Saya, Rosemary Toye, Philip G.

Objectives: The objective of this study was to assess whether cytotoxic T cells (CTL) generated by the live vaccine, known as “ITM Muguga cocktail”, which is used for the cattle disease East Cost fever (ECF) in Sub-Saharan Africa, showed a broad reactivity against many different strains of the ca...

Enlace original: https://cgspace.cgiar.org/handle/10568/92437

Investigación en Agricultura
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Steinaa, Lucilla ,  Svitek, Nicholas ,  Awino, Elias ,  Saya, Rosemary ,  Toye, Philip G. ,  [Cytotoxic T lymphocytes from cattle sharing the same MHC class I haplotype and immunized with live Theileria parva sporozoites differ in antigenic specificity] ,  Cytotoxic T lymphocytes from cattle sharing the same MHC class I haplotype and immunized with live Theileria parva sporozoites differ in antigenic specificity
Journal Article 2017-06-27

Autor: Mariner, Jeffrey C. Gachanja, J. Tindih, H.S. Toye, Philip G.

The research objective was to develop a thermostable vaccine against peste des petits ruminants (PPR), a morbilliviral disease of small ruminants targeted for eradication that is a major constraint on the livelihoods of the rural poor throughout much of Africa and Asia. Although existing PPR vacc...

Enlace original: https://cgspace.cgiar.org/handle/10568/81517

Investigación en Agricultura
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Mariner, Jeffrey C. ,  Gachanja, J. ,  Tindih, H.S. ,  Toye, Philip G. ,  [A thermostable presentation of the live, attenuated peste des petits ruminants vaccine in use in Africa and Asia] ,  A thermostable presentation of the live, attenuated peste des petits ruminants vaccine in use in Africa and Asia
Journal Article 2011-06-30

Autor: Patel, Ekta Lubembe, D.M. Gachanja, J. Mwaura, S. Spooner, P.R. Toye, Philip G.

The current Infection and Treatment Method of vaccination against East Coast fever comprises an inoculation of live Theileria parva sporozoites and simultaneous administration of oxytetracycline. Immunization with a combination of parasite types has been shown to provide broader protection than i...

Enlace original: https://cgspace.cgiar.org/handle/10568/3166

Investigación en Agricultura
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Patel, Ekta ,  Lubembe, D.M. ,  Gachanja, J. ,  Mwaura, S. ,  Spooner, P.R. ,  Toye, Philip G. ,  [Molecular characterization of live Theileria parva sporozoite vaccine stabilates reveals extensive genotypic diversity] ,  Molecular characterization of live Theileria parva sporozoite vaccine stabilates reveals extensive genotypic diversity
Journal Article 2012-06-15

Autor: Nene, Vishvanath Svitek, Nicholas Toye, Philip G. Golde, W.T. Barlow, J. Buus, Soren Nielsen, Morten

T cell responses contribute to immunity against many intracellular infections. There is, for example, strong evidence that major histocompatibility complex (MHC) class I-restricted cytotoxic T lymphocytes (CTLs) play an essential role in mediating immunity to East Coast fever (ECF), a fatal lymph...

Enlace original: https://cgspace.cgiar.org/handle/10568/16432

Investigación en Agricultura
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Nene, Vishvanath ,  Svitek, Nicholas ,  Toye, Philip G. ,  Golde, W.T. ,  Barlow, J. ,  Buus, Soren ,  Nielsen, Morten ,  [Designing bovine T cell vaccines via reverse immunology] ,  Designing bovine T cell vaccines via reverse immunology
Journal Article 2012-02-15

Autor: Steinaa, Lucilla Saya, R. Awino, Elias Toye, Philip G.

The protozoan parasite Theileria parva causes a usually fatal disease in cattle, known as East Coast fever. Cattle can be vaccinated by injecting live parasites simultaneously with long acting oxytetracycline (the Infection and Treatment Method, ITM). The immunity induced by ITM is believed to be...

Enlace original: https://cgspace.cgiar.org/handle/10568/16380

Investigación en Agricultura
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Steinaa, Lucilla ,  Saya, R. ,  Awino, Elias ,  Toye, Philip G. ,  [Cytotoxic T lymphocytes from cattle immunized against Theileria parva exhibit pronounced cross-reactivity among different strain-specific epitopes of the Tp1 antigen] ,  Cytotoxic T lymphocytes from cattle immunized against Theileria parva exhibit pronounced cross-reactivity among different strain-specific epitopes of the Tp1 antigen
Journal Article 2018-09-15

Autor: Sitt, T. Pelle, Roger Chepkwony, M.C. Morrison, W. Ivan Toye, Philip G.
Enlace original: https://cgspace.cgiar.org/handle/10568/98857

Investigación en Agricultura
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Sitt, T. ,  Pelle, Roger ,  Chepkwony, M.C. ,  Morrison, W. Ivan ,  Toye, Philip G. ,  [Theileria parva antigens recognized by CD8+ T cells show varying degrees of diversity in buffalo-derived infected cell lines] ,  Theileria parva antigens recognized by CD8+ T cells show varying degrees of diversity in buffalo-derived infected cell lines
Journal Article 2019-01-31

Autor: Patel, Ekta Mwaura, Stephen Giulio, Giuseppe di Cook, Elizabeth A.J. Lynen, Godelieve Toye, Philip G.
Enlace original: https://cgspace.cgiar.org/handle/10568/99527

Investigación en Agricultura
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Patel, Ekta ,  Mwaura, Stephen ,  Giulio, Giuseppe di ,  Cook, Elizabeth A.J. ,  Lynen, Godelieve ,  Toye, Philip G. ,  [Infection and treatment method (ITM) vaccine against East Coast fever: Reducing the number of doses per straw for use in smallholder dairy herds by thawing, diluting and refreezing already packaged vaccine] ,  Infection and treatment method (ITM) vaccine against East Coast fever: Reducing the number of doses per straw for use in smallholder dairy herds by thawing, diluting and refreezing already packaged vaccine
Brief 2015-05-01

Autor: Toye, Philip G. Ballantyne, Peter G.
Enlace original: https://cgspace.cgiar.org/handle/10568/66122

Investigación en Agricultura
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Toye, Philip G. ,  Ballantyne, Peter G. ,  [Improving the infection and treatment method vaccine for East Coast fever] ,  Improving the infection and treatment method vaccine for East Coast fever

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