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Bone morphogenetic protein (BMP) is an endogenous protein that has shown significant effects in the promotion of bone formation. BMP also has been described in the reconstruction of traumatic and pathological bone defects, including alveolar cleft, alveolar ridge augmentation, maxillary sinus ele...


Uribe, F.Cantín, M.Alister, J.P.Vilos, C.Fariña, R.Olate, S.[Bone Morphogenetic Protein and its Option as an Alveolar Cleft Treatment][Proteína Morfogenética Ósea y su Opción como Tratamiento de la Fisura Alveolar]Proteína Morfogenética Ósea y su Opción como Tratamiento de la Fisura Alveolar

Cabello-Verrugio, C.Vilos, C.Rodrigues-Diez, R.Estrada, L.[Oxidative stress in disease and aging: Mechanisms and therapies 2018]Oxidative stress in disease and aging: Mechanisms and therapies 2018

Nanotherapeutics is a promising field for numerous diseases and represents the forefront of modern medicine. In the present work, full atomistic computer simulations were applied to study poly(lactic acid) (PLA) nanoparticles conjugated with polyethylene glycol (PEG). The formation of this comple...


Matus, M.F.Ludueña, M.Vilos, C.Palomo, I.Mariscal, M.M.[Atomic-level characterization and cilostazol affinity of poly(lactic acid) nanoparticles conjugated with differentially charged hydrophilic molecules]Atomic-level characterization and cilostazol affinity of poly(lactic acid) nanoparticles conjugated with differentially charged hydrophilic molecules

Growth factors have great therapeutic potential for various disease therapy and tissue engineering applications. However, their clinical efficacy is hampered by low bioavailability, rapid degradation in vivo and non-specific biodistribution. Nanoparticle based delivery systems are being evaluated...


Choi, W.I.Sahu, A.Vilos, C.Kamaly, N.Jo, S.-M.Lee, J.H.Tae, G.[Bioinspired Heparin Nanosponge Prepared by Photo-crosslinking for Controlled Release of Growth Factors]Bioinspired Heparin Nanosponge Prepared by Photo-crosslinking for Controlled Release of Growth Factors

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