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Bloodstream forms (BSF) and procyclic culture forms (PCF) of African trypanosomes were incubated with a variety of lectins in vitro. Cessation of cell division and profound morphological changes were seen in procyclic forms but not in BSF after incubation with concanvavalin A (Con A). Wheat germ...


Pearson, T.W.Beecroft, R.P.Welburn, S.C.Ruepp, S.Roditi, I.Kuo-Yuan, H.Englund, P.T.Wells, C.W.Murphy, N.B.[The major cell surface glycoprotein procycline is a receptor for induction of a novel form of cell death in African trypanosomes in vitro]The major cell surface glycoprotein procycline is a receptor for induction of a novel form of cell death in African trypanosomes in vitro

Monoclonal antibodies (MAb) binding to Cowdria ruminantium elementary bodies (CB) were identified by enzyme-linked immunosorbent assay, and surface binding of one MAb (446.15) to intact CB was determined by immunofluorescence, immunogold labeling, and transmission electron microscopy. MAb 446.15 ...


Shompole, S.Rurangirwa, F.R.Wambugu, J.Sitienei, J.Mwangi, D.M.Musoke, A.J.Mahan, S.Wells, C.W.McGuire, T.C.[Monoclonal antibody binding to a surface exposed epitope on Cowdria ruminantium that is conserved among light strains]Monoclonal antibody binding to a surface exposed epitope on Cowdria ruminantium that is conserved among light strains

A monoclonal antibody (MAb)Tv27 employed in an antigen-detection enzyme immunosorbent assay (Ag-ELISA) for diagnosis of Trypanosoma vivax infection was shown to react with a T. vivax-specific protein of an approximate molecular weight of 10 kDa. This protein is diffusely distributed throughout th...


Masake, R.A.Ole-MoiYoi, O.K.Urakawa, T.Hirumi, H.Majiwa, P.A.O.Wells, C.W.Minja, S.H.Makau, J.M.Nantulya, V.M.[Immunological characterization and expression in Escherichia coli and Baculovirus systems of a Trypanosoma vivax antigen detected in the blood of infected animals]Immunological characterization and expression in Escherichia coli and Baculovirus systems of a Trypanosoma vivax antigen detected in the blood of infected animals

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