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Characterising the drug susceptibility of trypanosomes that are pathogenic for domestic livestock has for many years been carried out either in vivo, using large or small animals, or by using various in vitro cultivation methodologies (Peregrine, 1994). Thus, adaptation to, and multiplication of ...


Peregrine, A.S.Wells, C.W.Wilkes, J.M.[Methods for detection of drug resistance in trypanosomes - new developments?]Methods for detection of drug resistance in trypanosomes - new developments?

Theileria parva, an obligate intracellular protozoan parasite of cattle, causes East Coast fever, a fatal, lymphoproliferative disease, endemic in large areas of East and Central Africa. The mammalian-infective sporozoites of T. parva mature within the salivary glands of the ixodid tick Rhipiceph...


Wells, C.W.Awino, EliasMcKeever, Declan J.[Theileria parva sporozoite invasion and development within bovine dendritic cells]Theileria parva sporozoite invasion and development within bovine dendritic cells

Sequential changes in the blood and bone marrow (BM) were studied by light and transmission electron microscopy in three Boran and three Ndama cattle before and after a primary infection with Trypanosoma congolense IL 1180. Parasitaemia was essentially similar in the Borans and the Ndamas between...


Anosa, V.O.Logan-Henfrey, L.L.Wells, C.W.[Bone marrow and macrophage functions as determinants of bovine trypanotolerance]Bone marrow and macrophage functions as determinants of bovine trypanotolerance

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