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Six new cyclodiprenyl phenols were synthesized by direct coupling of perillyl alcohol and the appropriate phenol. Their structures were established by IR, HRMS and mainly NMR. Three human cancer cell lines-breast (MCF-7), prostate (PC-3) and colon (HT-29)-were used in antiproliferative assays, wi...


Said, B.Montenegro, I.Valenzuela, M.Olguín, Y.Caro, N.Werner, E.Godoy, P.Villena, J.Madrid, A.[Synthesis and antiproliferative activity of new cyclodiprenyl phenols against select cancer cell lines]Synthesis and antiproliferative activity of new cyclodiprenyl phenols against select cancer cell lines

An efficient synthesis of a series of 4-oxyalkyl-isocordoin analogues (2–8) is reported for the first time. Their structures were confirmed by1H-NMR,13C-NMR, and HRMS. Their anti-oomycete activity was evaluated by mycelium and spores inhibition assay against two selected pathogenic oomycetes stra...


Escobar, B.Montenegro, I.Villena, J.Werner, E.Godoy, P.Olguín, Y.Madrid, A.[Hemi-Synthesis and Anti-Oomycete Activity of Analogues of Isocordoin]Hemi-Synthesis and Anti-Oomycete Activity of Analogues of Isocordoin

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