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This review of the prospects for developing an immunization procedure against trypanosomiasis explores a number of promising avenues of research. Part I covers variable antigen types (VATs); metacyclic antigens; in vivo and in vitro attenuation; and molecular and genetic engineering. Part II, to ...
Reviews prospects of vaccination against African trypanosomiasis, mentioning constraints in developing a vaccine, and current knowledge on the molecular biology of the trypanosome and on antigenic variation with respect to possible future vaccines. Describes possible regimes for immunological int...
In part I of this review of the prospects of vaccination against African trypanosomiasis, contained in the previous issue of World Animal Review, the constraints in developing a vaccine were discussed and current knowledge on the molecular biology of the trypanosome and on antigenic variation wit...
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